Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
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Journal ArticleDOI
The Neurobiologist's Guide to Structural Biology: A Primer on Why Macromolecular Structure Matters and How to Evaluate Structural Data
TL;DR: This primer aims to help neurobiologists understand approaches for probing macromolecular structure and where the limits and challenges remain.
Journal ArticleDOI
Dengue virus nonstructural protein 5 adopts multiple conformations in solution.
Cecile Bussetta,Kyung H. Choi +1 more
TL;DR: The multiple conformations of NS5 observed in solution are interpreted as resulting from weak interactions between the two NS5 domains and flexibility of the linker in the absence of other components of the replication complex.
Journal ArticleDOI
Random coil negative control reproduces the discrepancy between scattering and FRET measurements of denatured protein dimensions.
Herschel M. Watkins,Anna J. Simon,Tobin R. Sosnick,Everett A. Lipman,Rex P. Hjelm,Kevin W. Plaxco +5 more
TL;DR: This work explores the origins of a discrepancy in the relationship between proteins unfolded under physiological conditions and those unfolded by chemical denaturation using PEG as a negative control, and indicates that the polymer’s dimensions are denaturant-independent.
Journal ArticleDOI
Binding of rabies virus polymerase cofactor to recombinant circular nucleoprotein-RNA complexes.
Euripedes A. Ribeiro,Cedric Leyrat,Francine C. A. Gérard,Aurélie A. V. Albertini,Caroline Falk,Rob W.H. Ruigrok,Marc Jamin +6 more
TL;DR: A structural model is in agreement with available biochemical data and provides new insights on the mechanism of attachment of the polymerase complex to the NC template.
Journal ArticleDOI
Memprot: a program to model the detergent corona around a membrane protein based on SEC–SAXS data
TL;DR: Systematic SAXS simulations have been analysed over a wide range of parameters in order to better understand the detergent corona around a membrane protein.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.