Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
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Stimulation of the maltose transporter ATPase by unliganded maltose binding protein
TL;DR: Results indicate that stimulation of the MalFGK(2) ATPase by unligandedMBP does not proceed through a closed conformation and instead must operate through a different mechanism than stimulation by liganded MBP.
Journal ArticleDOI
Solution scattering approaches to dynamical ordering in biomolecular systems.
TL;DR: In this review, recent progress and trends of SAXS and SANS are introduced from the point of view of instrumentation and analysis, touching on general features and standard methods of small-angle scattering.
Journal ArticleDOI
Probing dimerization and structural flexibility of mammalian lipoxygenases by small-angle X-ray scattering.
Weifeng Shang,Igor Ivanov,Dmitri I. Svergun,Oleg Y. Borbulevych,Ansari M. Aleem,Sabine Stehling,Jerzy Jankun,Jerzy Jankun,Hartmut Kühn,Ewa Skrzypczak-Jankun +9 more
TL;DR: R-12/15LOX functions as a monomer that dominates in solution and all three mammalian isozymes show a high level of flexibility not only for the PLAT domain but also for other subdomains of the catalytic part in TLS (translation, libration, and screw rotation) analysis and hp-12LOX in SAXS.
Journal ArticleDOI
The structure of vanin 1: a key enzyme linking metabolic disease and inflammation
Ykelien L. Boersma,Janet Newman,Timothy E. Adams,Nathan Cowieson,Guy Y. Krippner,Kiymet Bozaoglu,Thomas S. Peat +6 more
TL;DR: The X-ray crystal structure of human vanin 1 at 2.25 Å resolution is presented, which is the first reported structure from the vanin family, and sheds light on how the enzymatic activity is regulated by a novel allosteric mechanism at a domain interface.
Journal ArticleDOI
Solution Structure of the Chicken Skeletal Muscle Troponin Complex Via Small-angle Neutron and X-ray Scattering
William A. King,Deborah B. Stone,Peter A. Timmins,Theyencheri Narayanan,Alex A.M. von Brasch,Robert A. Mendelson,Paul M. G. Curmi,Paul M. G. Curmi +7 more
TL;DR: A rigid-body Monte Carlo optimization procedure was used to yield models of chicken skeletal muscle troponin, in solution, in the presence and in the absence of regulatory calcium, and these models show significant differences when compared to the cardiac Troponin crystal structure in the +Ca2+ state.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.