Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
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Biological role and structural mechanism of twinfilin–capping protein interaction
Sandra Falck,Ville O. Paavilainen,Martin A. Wear,J. Günter Grossmann,John A. Cooper,Pekka Lappalainen +5 more
TL;DR: The binding of twinfilin to CP does not affect the binding of either protein to actin, and site‐directed mutagenesis studies revealed that the CP‐binding site resides in the conserved C‐terminal tail region of twin Filin.
Journal ArticleDOI
Pressure Denaturation of Staphylococcal Nuclease Studied by Neutron Small-Angle Scattering and Molecular Simulation
TL;DR: The results indicate that the globular structure of SN is retained across the folding/unfolding transition although this structure is less compact and elongated relative to the native structure.
Journal ArticleDOI
A conserved mode of protein recognition and binding in a ParD-ParE toxin-antitoxin complex
Kevin M. Dalton,Sean Crosson +1 more
TL;DR: It is demonstrated that ParD antitoxin is dimeric, stably folded, and largely helical when not bound to ParE toxin, demonstrating that the paradigmatic model in which antitoxin undergoes a disorder-to-order transition upon toxin binding does not apply to this chromosomal ParD-ParE TA system.
Journal ArticleDOI
Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
Hamed Kooshapur,Nila Roy Choudhury,Bernd Simon,Max Muehlbauer,Max Muehlbauer,Alexander Jussupow,Alexander Jussupow,Noemi Fernandez,Alisha N Jones,André Dallmann,Frank Gabel,Carlo Camilloni,Carlo Camilloni,Gracjan Michlewski,Javier F. Cáceres,Michael Sattler +15 more
TL;DR: It is shown that hnRNP A1 forms a 1:1 complex with pri-mir-18a where both RNA recognition motifs (RRMs) bind to cognate RNA sequence motifs in the terminal loop of pri-Mir-18A.
Journal ArticleDOI
Microsecond Hydrophobic Collapse in the Folding of Escherichia coli Dihydrofolate Reductase, an α/β-Type Protein
Munehito Arai,Elena Kondrashkina,Can Kayatekin,C. Robert Matthews,Masahiro Iwakura,Osman Bilsel +5 more
TL;DR: The protein folding trajectories constructed by comparing the development of the compactness and the secondary structure suggest that the specific hydrophobic collapse model rather than the framework model better explains the experimental observations.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.