Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
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The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled‐coil
Rebecca Conners,Darryl J. Hill,Elena Borodina,Christopher R. Agnew,Sarah J. Daniell,Nicholas M. Burton,Richard B. Sessions,Anthony R. Clarke,Lucy E. Catto,Donna Lammie,Tim J Wess,R. Leo Brady,Mumtaz Virji +12 more
TL;DR: X‐ray crystallography is shown to show that the CEACAM1 receptor‐binding region of UspA1 unusually consists of an extended, rod‐like left‐handed trimeric coiled‐coil, explaining how USpA1 can engage CEACam1 at a site far distant from its head group, permitting closer proximity of the respective cell surfaces during infection.
Journal ArticleDOI
Pathways for virus assembly around nucleic acids.
TL;DR: In this article, the authors use computer simulations to characterize assembly over a wide range of capsid protein-protein interaction strengths and solution ionic strengths, and find that assembly pathways can be categorized into two classes, in which intermediates are either predominantly ordered or disordered.
Journal ArticleDOI
γH2A binds Brc1 to maintain genome integrity during S-phase
Jessica S. Williams,R. Scott Williams,Claire L. Dovey,Grant Guenther,John A. Tainer,John A. Tainer,Paul Russell +6 more
TL;DR: From these results, Brc1 docking to γH2A emerges as a critical chromatin‐specific response to replication‐associated DNA damage.
Journal ArticleDOI
Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
Lorenzo Alamo,Dan Qi,Willy Wriggers,Antonio Pinto,Jingui Zhu,Aivett Bilbao,Richard E. Gillilan,Songnian Hu,Raúl Padrón +8 more
TL;DR: The new model, PDB 3JBH, explains the structural origin of the ATP turnover rates detected in relaxed tarantula muscle by ascribing the veryslow rate to docked unphosphorylated heads, the slow rate to phosphorylated docked heads, and the fast rate to phosphate-based undocked heads.
Journal ArticleDOI
Role of histone tails in the conformation and interactions of nucleosome core particles.
TL;DR: The attractive interactions do not emerge in the absence of the tails, which validates the proposed hypothesis.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.