Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
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Journal ArticleDOI
The Structure and Stability of the Disulfide-Linked γS-Crystallin Dimer Provide Insight into Oxidation Products Associated with Lens Cataract Formation.
David C. Thorn,Aidan B. Grosas,Peter D. Mabbitt,Nicholas J. Ray,Colin J. Jackson,John A. Carver +5 more
TL;DR: The structure of a disulfide-linked dimer of human γS-crystallin that was obtained via oxidation of C24 is described and it is implied that early-onset and age-related forms of the disease share comparable development pathways.
Journal ArticleDOI
Molecular structure of human synaptonemal complex protein SYCE1
Orla M. Dunne,Owen R. Davies +1 more
TL;DR: The structure of human SYCE1 is reported through solution biophysical methods including multi-angle light scattering and small-angle X-ray scattering to achieve structural stability of the SC central element.
Journal ArticleDOI
The new NCPSS BL19U2 beamline at the SSRF for small-angle X-ray scattering from biological macromolecules in solution.
Na Li,Li Xiuhong,Wang Yuzhu,Guangfeng Liu,Ping Zhou,Hongjin Wu,Chunxia Hong,Bian Fenggang,Rongguang Zhang +8 more
TL;DR: A new biological small-angle X-ray scattering beamline (BioSAXS, BL19U2) at the Shanghai Synchrotron Radiation Facility (SSRF) is dedicated exclusively to small-angles scattering experiments from biological macromolecules in solution, the first in China to serve the rapidly increasing biology communities.
Journal ArticleDOI
Analysis of Self-Associating Proteins by Singular Value Decomposition of Solution Scattering Data
Tim E. Williamson,Bruce A. Craig,Elena Kondrashkina,Chris Bailey-Kellogg,Chris Bailey-Kellogg,Alan M. Friedman +5 more
TL;DR: A method by which a single experiment can reveal both association model (pathway and constants) and low-resolution structures of a self-associating system and the reconstructed scattering curves are fundamental to further analysis.
Journal ArticleDOI
The role of nanometer-scaled ligand patterns in polyvalent binding by large mannan-binding lectin oligomers.
Louise C. Gjelstrup,Jørn Døvling Kaspersen,Manja A. Behrens,Jan Skov Pedersen,Steffen Thiel,Peter Kingshott,Peter Kingshott,Cristiano L. P. Oliveira,Cristiano L. P. Oliveira,Nicole M. Thielens,Thomas Vorup-Jensen +10 more
TL;DR: An analysis of the binding to neoglycoprotein-coated surfaces by size-fractionated human MBL oligomers studied with small-angle x-ray scattering and surface plasmon resonance spectroscopy demonstrated that the MBL-binding kinetics are critically dependent on structural characteristics on the nanometer scale.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.