Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
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Journal ArticleDOI
Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6
Ekaterina Baranova,Stephen D. Weeks,Steven Beelen,Olesya V. Bukach,Nikolai B. Gusev,Sergei V. Strelkov +5 more
TL;DR: Using SAXS, it is shown that it is possible to discriminate between different putative registers of the β7/β7 interface, with the results indicating that, under physiological conditions, there is only a single register of the strands for both proteins.
Journal ArticleDOI
Consequences of chirality on the dynamics of a water-soluble supramolecular polymer.
Matthew B. Baker,Lorenzo Albertazzi,Ilja K. Voets,Christianus M. A. Leenders,Anja R. A. Palmans,Giovanni M. Pavan,E. W. Meijer +6 more
TL;DR: This report represents the first observation of a structure/property relationship with regard to equilibrium dynamics in water-soluble supramolecular polymers.
Journal ArticleDOI
Biological small-angle X-ray scattering facility at the Stanford Synchrotron Radiation Laboratory
TL;DR: The beamline 4-2 at the Stanford Synchrotron Radiation Laboratory is a small-angle X-ray scattering/diffraction facility dedicated to structural studies on mostly non-crystalline biological systems.
Journal ArticleDOI
IRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly
Ryan Ferrao,Ryan Ferrao,Ryan Ferrao,Hao Zhou,Yibing Shan,Qun Liu,Qiubai Li,Qiubai Li,David E. Shaw,David E. Shaw,Xiaoxia Li,Hao Wu,Hao Wu,Hao Wu +13 more
TL;DR: It is shown that unphosphorylated IRAK4 dimerizes in solution with a KD of 2.5 μM and that Myddosome assembly greatly enhances IRAK 4 kinase domain (KD) autophosphorylation at sub-KD concentrations, and identifies a mechanism for oligomerization-driven allosteric autoactivation of IRAk4 that may be general to other kinases activated by autoph phosphorylation.
Journal ArticleDOI
A Structural Study of CESA1 Catalytic Domain of Arabidopsis Cellulose Synthesis Complex: Evidence for CESA Trimers
Venu Gopal Vandavasi,Daniel K. Putnam,Qiu Zhang,Loukas Petridis,William T. Heller,B. Tracy Nixon,Candace H. Haigler,Udaya C. Kalluri,Leighton Coates,Paul Langan,Jeremy C. Smith,Jens Meiler,Hugh O'Neill +12 more
TL;DR: The “hexamer of trimers” model for the rosette cellulose synthesis complex that synthesizes an 18-chain cellulose microfibril as its fundamental product strongly supports the number of cellulose synthase proteins in this large multisubunit transmembrane protein complex.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.