Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
More filters
Journal ArticleDOI
Insights into EB1 structure and the role of its c-terminal domain for discriminating microtubule tips from the lattice
Rubén M. Buey,Renu Mohan,Kris Leslie,Thomas Walzthoeni,Thomas Walzthoeni,John Missimer,Andreas Menzel,Saša Bjelić,Katja Bargsten,Ilya Grigoriev,Ihor Smal,Erik Meijering,Ruedi Aebersold,Ruedi Aebersold,Anna Akhmanova,Michel O. Steinmetz +15 more
TL;DR: EBs, key microtubule (MT) tip–tracking proteins, are elongated molecules with two interacting calponin homology (CH) domains, an arrangement reminiscent of MT- and actin-binding CH proteins.
Journal ArticleDOI
Analysis of rapid, large-scale protein quaternary structural changes: time-resolved X-ray solution scattering of Nudaurelia capensis omega virus (NomegaV) maturation.
TL;DR: In this paper, a time-resolved small-angle X-ray scattering (TR-SAXS) was used to study the kinetics of a large conformational change that occurs during the maturation of an icosahedral virus.
Journal ArticleDOI
Activation of the LicT Transcriptional Antiterminator Involves a Domain Swing/Lock Mechanism Provoking Massive Structural Changes
Marc Graille,Cong-Zhao Zhou,Véronique Receveur-Bréchot,Bruno Collinet,Nathalie Declerck,Herman van Tilbeurgh +5 more
TL;DR: The results suggest that PRD2 is highly mobile in the native protein, whereas it is locked upon activation by phosphorylation, as well as the molecular solution structure of the full-length protein deduced from small angle x-ray scattering.
Journal ArticleDOI
NMR and small-angle scattering-based structural analysis of protein complexes in solution
TL;DR: The utility and computational approaches of combining solution state NMR with small-angle X-ray and Neutron scattering experiments for structural analysis of large protein complexes is reviewed and recent progress in experimental and computational approach of combining NMR and SAS is discussed and illustrated.
Journal ArticleDOI
Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Bert J. C. Janssen,Lucio Gomes,Roman I. Koning,Dmitri I. Svergun,Abraham J. Koster,David C. Fritzinger,Carl-Wilhelm Vogel,Piet Gros +7 more
TL;DR: In insights into formation of convertases, a possible dynamic equilibrium between a ‘loading’ and ‘activation’ state of the pro‐convertase may explain the observed difference between the crystal structure of CVFB and the EM structure of C3bB.
References
More filters
Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.