Journal ArticleDOI
CRYSOL : a program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
TLDR
In this paper, a program for evaluating the solution scattering from macromolecules with known atomic structure is presented, which uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell.Abstract:
A program for evaluating the solution scattering from macromolecules with known atomic structure is presented. The program uses multipole expansion for fast calculation of the spherically averaged scattering pattern and takes into account the hydration shell. Given the atomic coordinates (e.g. from the Brookhaven Protein Data Bank) it can either predict the solution scattering curve or fit the experimental scattering curve using only two free parameters, the average displaced solvent volume per atomic group and the contrast of the hydration layer. The program runs on IBM PCs and on the major UNIX platforms.read more
Citations
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Journal ArticleDOI
Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Eric Thierry,Delphine Guilligay,Jan Kosinski,Thomas Bock,Stephanie Gaudon,Adam Round,Alexander Pflug,Narin Hengrung,Kamel El Omari,Florence Baudin,Darren J. Hart,Martin Beck,Stephen Cusack +12 more
TL;DR: A FluB polymerase structure with a bound complementary cRNA 5′ end that exhibits a major rearrangement of the subdomains within the C-terminal two-thirds of PB2 (PB2-C) is presented.
Journal ArticleDOI
An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions.
Noboru Ishiyama,Nobutoshi Tanaka,Kentaro Abe,Yoo Jeong Yang,Yazan M. Abbas,Masataka Umitsu,Bhushan Nagar,Stephanie A. Bueler,John L. Rubinstein,Masatoshi Takeichi,Mitsuhiko Ikura,Mitsuhiko Ikura +11 more
TL;DR: A molecular switch mechanism involving multistate conformational changes of α-catenin is proposed, driven by actomyosin-generated tension to dynamically regulate the vinculin-assisted linkage between adherens junctions and the actin cytoskeleton.
Journal ArticleDOI
Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis.
David S. Shin,Michael DiDonato,David P. Barondeau,Greg L. Hura,Chiharu Hitomi,J. Andrew Berglund,Elizabeth D. Getzoff,S. Craig Cary,S. Craig Cary,John A. Tainer +9 more
TL;DR: Identification, cloning, characterization, X-ray scattering, and crystal structure determinations show that A. pompejana SOD (ApSOD) is superstable, homologous, and informative, and suggest that the eukaryote provides macromolecules highly similar to those from humans, but with enhanced stability more suitable for scientific and medical applications.
Journal ArticleDOI
Structure of bacterial cellulose synthase subunit D octamer with four inner passageways
Song-Qing Hu,Yong-Gui Gao,Yong-Gui Gao,Kenji Tajima,Naoki Sunagawa,Yong Zhou,Shin Kawano,Takaaki Fujiwara,Takanori Yoda,Daisuke Shimura,Yasuharu Satoh,Masanobu Munekata,Isao Tanaka,Min Yao +13 more
TL;DR: The cellulose synthesizing terminal complex in Acetobacter xylinum spans the outer and inner cell membranes to synthesize and extrude glucan chains, which are assembled into subelementary fibrils and further into a ribbon.
Journal ArticleDOI
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Yi Li,Dimitri Y. Chirgadze,Victor M. Bolanos-Garcia,Bancinyane L. Sibanda,Owen R. Davies,Peter Ahnesorg,Stephen P. Jackson,Tom L. Blundell +7 more
TL;DR: The crystal structure of the XLF homodimer at 2.3 Å resolution is reported, confirming the predicted structural similarity to XRCC4 and demonstrating interactions between dimers of XLF and XR CC4 by surface plasmon resonance and analysing these in terms of surface properties, amino‐acid conservation and mutations in immunodeficient patients.
References
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Book
International tables for X-ray crystallography
Norman Fordyce McKerron Henry,Lonsdale, Kathleen, Dame,John S. Kasper,Caroline H. MacGillavry,Gerard D. Rieck,James A. Ibers,Walter C. Hamilton +6 more
Angular Momentum in Quantum Mechanics
TL;DR: In this paper, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.
Book
Angular Momentum in Quantum Mechanics
TL;DR: In this article, the angular momentum, one of the most fundamental quantities in all of quantum mechanics, is introduced and a concise introduction to its application in atomic, molecular, and nuclear physics is provided.