Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
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TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
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Virtual reality assessment of functional capacity in people with Schizophrenia: Associations with reduced emotional experience and prediction of functional outcomes.
TL;DR: The differential validity of solitary vs. socially relevant simulations was supported by differences in correlates, suggesting that assessments with a focus on performance of simulated socially relevant tasks could be developed.
Journal ArticleDOI
Gender differences of neurocognitive functioning in patients with first-episode schizophrenia in China
Cheng-cheng Pu,Yujia Qiu,Tianhang Zhou,Fude Yang,Zheng Lu,Chuanyue Wang,Hong Deng,Jingping Zhao,Chuan Shi,Xin Yu +9 more
TL;DR: Both female patients with first-episode schizophrenia andFemale patients with clinically stable schizophrenia performed better than male patients, and gender was an independent influence factor for the verbal learning and memory domain.
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Negative symptom dimensions differentially impact on functioning in individuals at-risk for psychosis.
Wing Chung Chang,H C Lee,Sherry Chan,S Y Chiu,H M Lee,Kit Wa Chan,M C Wong,K L Chan,WS Yeung,Lam Wai Choy,S Y Chong,M W Siu,T L Lo,W C Yan,M K Ng,L T Poon,P F Pang,W C Lam,Y C Wong,W S Chung,Y M Mo,S Y Lui,L M Hui,Eric Y.H. Chen +23 more
TL;DR: This dissertation aims to provide a history of psychiatry in Hong Kong from 1950 to 1997, a period chosen in order to explore its roots as well as specific cases up to and including the year in which psychiatry was introduced to Hong Kong.
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Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions
TL;DR: Increases in extracellular glycine, possibly through actions on the glycine allosteric site on the NMDA receptor, may be a useful strategy for treating motivational dysfunctions in humans.
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The interplay between functioning problems and symptoms in first episode of psychosis: An approach from network analysis
Ana Izquierdo,Maria Cabello,Itziar Leal,Blanca Mellor-Marsá,Miriam Ayora,María Fe Bravo-Ortiz,Roberto Rodriguez-Jimenez,Angela Ibáñez,Karina S. MacDowell,Norberto Malpica,Marina Díaz-Marsá,Enrique Baca-García,Enrique Baca-García,Natalia E. Fares-Otero,Helena Melero,Pilar Lopez-Garcia,Covadonga M. Díaz-Caneja,Celso Arango,José Luis Ayuso-Mateos,Julia García-Albea,Dolores Saiz-González,Manuel Durán-Cutilla,Jessica Merchán-Naranjo,Roberto Mediavilla-Torres,Ainoa Muñoz-Sanjose,Luis Sanchez-Pastor,Mónica Dompablo,Patricia Fernández-Martín,Leticia León-Quismondo,Juan C. Leza,Pablo Puras-Rico,Lucía Albarracin-García +31 more
TL;DR: In this article, the interplay between specific clinical symptoms and particular areas of functioning in first-episode psychosis (FEP) using network analysis methods has been assessed, and the most important nodes were "conceptual disorganization", "emotional withdrawal", "lack of spontaneity and flow of conversation", "delusions", "unusual thought content", "dealing with strangers", and "poor rapport".
References
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
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Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
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Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
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Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
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