Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
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TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
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The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies
Roman Kotov,Robert F. Krueger,David Watson,Thomas M. Achenbach,Robert R. Althoff,R. Michael Bagby,Timothy A. Brown,William T. Carpenter,Avshalom Caspi,Lee Anna Clark,Nicholas R. Eaton,Miriam K. Forbes,Kelsie T. Forbush,David Goldberg,Deborah S. Hasin,Steven E. Hyman,Masha Y. Ivanova,Donald R. Lynam,Kristian E. Markon,Joshua D. Miller,Terrie E. Moffitt,Leslie C. Morey,Stephanie N. Mullins-Sweatt,Johan Ormel,Christopher J. Patrick,Darrel A. Regier,Leslie Rescorla,Camilo J. Ruggero,Douglas B. Samuel,Martin Sellbom,Leonard J. Simms,Andrew E. Skodol,Tim Slade,Susan C. South,Jennifer L. Tackett,Irwin D. Waldman,Monika A. Waszczuk,Thomas A. Widiger,Aidan G. C. Wright,Mark Zimmerman +39 more
TL;DR: The HiTOP promises to improve research and clinical practice by addressing the aforementioned shortcomings of traditional nosologies and provides an effective way to summarize and convey information on risk factors, etiology, pathophysiology, phenomenology, illness course, and treatment response.
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Definition and description of schizophrenia in the DSM-5
Rajiv Tandon,Wolfgang Gaebel,M Deanna,Juan R. Bustillo,Raquel E. Gur,Stephan Heckers,Dolores Malaspina,Dolores Malaspina,Michael John Owen,Susan K. Schultz,Ming T. Tsuang,Ming T. Tsuang,Ming T. Tsuang,Jim van Os,Jim van Os,William T. Carpenter +15 more
TL;DR: The essence of the broad DSM-IV definition of schizophrenia is retained and changes in its definition should improve diagnosis and characterization of individuals with schizophrenia and facilitate measurement-based treatment and concurrently provide a more useful platform for research that will elucidate its nature.
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A Review of Reward Processing and Motivational Impairment in Schizophrenia
TL;DR: Research on reward processing in schizophrenia has begun to provide important insights into the cognitive and neural mechanisms associated with motivational impairments, and suggestions for novel behavioral intervention strategies that make use of external cues, reinforcers, and mobile technology are discussed.
Journal ArticleDOI
The influence of illness-related variables, personal resources and context-related factors on real-life functioning of people with schizophrenia
Silvana Galderisi,Alessandro Rossi,Paola Rocca,Alessandro Bertolino,Armida Mucci,Paola Bucci,Paola Rucci,Dino Gibertoni,Eugenio Aguglia,Mario Amore,Antonello Bellomo,Massimo Biondi,Roberto Brugnoli,Liliana Dell'Osso,Diana De Ronchi,Gabriella Di Emidio,Massimo Di Giannantonio,Andrea Fagiolini,Carlo Marchesi,Palmiero Monteleone,Lucio Oldani,Federica Pinna,Rita Roncone,Emilio Sacchetti,Paolo Santonastaso,Alberto Siracusano,Antonio Vita,Patrizia Zeppegno,Mario Maj +28 more
TL;DR: The observed complex associations among investigated predictors, mediators and real‐life functioning strongly suggest that integrated and personalized programs should be provided as standard treatment to people with schizophrenia.
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The current conceptualization of negative symptoms in schizophrenia.
TL;DR: The assessment of the negative symptom dimension has recently improved, but even current expert consensus‐based instruments diverge on several aspects and the use of objective measures might contribute to overcome uncertainties about the reliability of rating scales, but these measures require further investigation and validation.
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