Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
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TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
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Functional Impairments and Theory of Mind Deficits in Schizophrenia: A Meta-analysis of the Associations
TL;DR: In this article, a meta-analysis was conducted to document and compare the magnitude of the associations between theory of mind and different domains of functioning (social functioning, productive activities, and instrumental activities of daily living), each assessed separately for functional performance and functional outcome and different aspects of functioning in schizophrenia.
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Cerebral blood flow in striatal regions is associated with apathy in patients with schizophrenia
Karoline Schneider,Lars Michels,Matthias N. Hartmann-Riemer,Achim Burrer,Philippe N. Tobler,Philipp Stämpfli,Matthias Kirschner,Erich Seifritz,Stefan Kaiser +8 more
TL;DR: The main finding was a specific association between increased striatal rCBF and the negative symptom dimension of apathy, which further support the separate assessment of apathetic and diminished expression when investigating the neural basis of negative symptoms.
Journal ArticleDOI
The neural correlates of apathy in schizophrenia: An exploratory investigation.
Fernando Caravaggio,Gagan Fervaha,Gagan Fervaha,Mahesh Menon,Gary Remington,Ariel Graff-Guerrero,Ariel Graff-Guerrero,Philip Gerretsen +7 more
TL;DR: The present findings set the stage for future larger‐scale studies confirming the structural and neurochemical substrates of apathy in schizophrenia, and demonstrate that these GM associations are distinct from those with Affective Flattening.
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Prediction of motivational impairment: 12-month follow-up of the randomized-controlled trial on extended early intervention for first-episode psychosis
Wing Chung Chang,Vivian Wing Yan Kwong,Gloria Hoi Kei Chan,Olivia Tsz Ting Jim,Emily Sin Kei Lau,Clm Hui,Sherry Kit Wa Chan,Edwin Ho Ming Lee,Eric Y.H. Chen +8 more
TL;DR: A potentially critical therapeutic role of an extended specialized EI on alleviating motivational impairment in FEP patients is indicated, and Hierarchical multiple regression analysis revealed that Extended EI and lower levels of DE independently predicted better outcome on 12-month amotivation.
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Trends in the Study of Motivation in Schizophrenia: A Bibliometric Analysis of Six Decades of Research (1956-2017).
TL;DR: A significant growth trend in literature production, especially since the 2000s, with reward as the main term studied is revealed, with questionnaires identified as the preferred instrument to assess motivation in patients with schizophrenia.
References
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Book
Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
Book
Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
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