Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
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TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
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What Factors Influence the Decision to Share Suicidal Thoughts? A Multilevel Social Network Analysis of Disclosure Among Individuals with Serious Mental Illness
TL;DR: Results suggest that "targeted" gatekeeper training may be a promising strategy and reveal relational characteristics to identify "high-probability confidants" in adults with schizophrenia, bipolar disorder, or major depressive disorder.
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EPA guidance on assessment of negative symptoms in schizophrenia.
Silvana Galderisi,Armida Mucci,Sonia Dollfus,Merete Nordentoft,Peter Falkai,Stefan Kaiser,Giulia Maria Giordano,A Vandevelde,Mette Ødegaard Nielsen,Louise Birkedal Glenthøj,Michel Sabe,P. Pezzella,István Bitter,Wolfgang Gaebel +13 more
TL;DR: In this paper, the authors provide a systematic review of the evidence and elaborate several recommendations for the conceptualization and assessment of negative symptoms in clinical trials and practice, and they also encourage clinicians to use second-generation scales, at least to complement first-generation ones.
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Social relationships in young adults at ultra high risk for psychosis.
TL;DR: It is suggested that youth at high-risk of developing psychosis have fewer and poorer quality social relationships and interventions that focus on increasing the quantity and quality of young adults' social networks may be beneficial for this population.
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Neurobiological basis of motivational deficits in psychopathology.
TL;DR: The literature suggests that research on the neurobiology of motivational dysfunction in psychopathology could inform the development of novel and more effective treatments for a range of CNS disorders.
Journal ArticleDOI
Defining and measuring negative symptoms of schizophrenia in clinical trials
TL;DR: Two newer scales, the Brief Negative Symptom Scale (BNSS) and the Clinical Assessment Interview for Negative Symptoms (CAINS) were developed following a National Institute of Mental Health consensus meeting and addressed some of the shortcomings of earlier instruments.
References
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Book
Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
Book
Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
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