Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
Reads0
Chats0
TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
Citations
More filters
Journal ArticleDOI
From apathy to addiction: Insights from neurology and psychiatry.
TL;DR: The dopamine theory of addiction is recast based on the idea that tonic dopamine may index a continuous phenotype that goes from apathy to impulsivity and compulsivity, which would make individuals vulnerable to drug reinforcement and cue-induced craving.
Journal ArticleDOI
Relationship Between Persistent Negative Symptoms and Findings of Neurocognition and Neuroimaging in Schizophrenia.
Ezgi Ince,Alp Üçok +1 more
TL;DR: This review focuses on neural correlates and neurocognitive associations of PNS, and discusses PNS findings available to date.
Journal ArticleDOI
A meta-analytic review of self-reported, clinician-rated, and performance-based motivation measures in schizophrenia: Are we measuring the same "stuff"?
TL;DR: A series of meta-analyses that summarize the relationships between methods of motivation measurement in 45 studies of people with schizophrenia is presented in this article. But, the overall mean effect size between self-reported and clinician-rated motivation measures was negligible and non-significant.
Journal ArticleDOI
Predicting the future in schizophrenia: The discrepancy between anticipatory and consummatory pleasure.
TL;DR: A new task examining the discrepancy between anticipated and experienced pleasure is introduced and its potential usefulness to characterise the pleasure deficit in people with schizophrenia is investigated.
Journal ArticleDOI
Transformed PANSS Factors Intended to Reduce Pseudospecificity Among Symptom Domains and Enhance Understanding of Symptom Change in Antipsychotic-Treated Patients With Schizophrenia
TL;DR: The results confirmed that transformed PANSS factors retained a high degree of specificity, thus validating that low between-factor correlations are a reliable property of the USPM when transforming PANSS data from a variety of clinical trial data sets.
References
More filters
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Book
Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
Book
Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
Related Papers (5)
The Structure of Negative Symptoms Within Schizophrenia: Implications for Assessment
Jack J. Blanchard,Alex S. Cohen +1 more