Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
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TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
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The association of neurocognitive impairment with diminished expression and apathy in schizophrenia.
Matthias N. Hartmann-Riemer,Oliver M. Hager,Matthias Kirschner,Martin Bischof,Agne Kluge,Erich Seifritz,Stefan Kaiser +6 more
TL;DR: It is found that diminished expression significantly related to neurocognitive impairment, while severity of apathy symptoms was not directly associated with neurocognition, which indicates that cognitive remediation therapy might be helpful to ameliorate expressive deficits.
Journal ArticleDOI
Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD
TL;DR: The hypothesis that central histamine (HA) plays a significant role in the regulation of neuroinflammatory processes of microglia functions in numerous neuropsychiatric diseases, i.e., ASD, AD, SCH, Schizophrenia, epilepsy, and BPSD is examined.
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Common Taxonomy of Traits and Symptoms: Linking Schizophrenia Symptoms, Schizotypy, and Normal Personality.
TL;DR: This is the first study to show that symptoms of psychosis, schizotypy, and normal personality reflect the same underlying dimensions, and underscores the importance of traits to understanding these disorders.
Journal ArticleDOI
Persistent negative symptoms after first episode schizophrenia: A 2-year follow-up study.
Alp Üçok,Ceylan Ergül +1 more
TL;DR: The findings suggest that PNS has specific predictors and effect on the course of illness after first-episode schizophrenia.
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Reward anticipation and trait anhedonia: An electrophysiological investigation in subjects with schizophrenia.
TL;DR: Findings indicate that anhedonia and avolition are partially independent constructs in subjects with schizophrenia, and SCZ are unable to integrate the incentive magnitude and reward value of future events in the context of their ongoing task.
References
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Book
Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
Book
Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
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