Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
Citations
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Large-Scale Evaluation of the Positive and Negative Syndrome Scale (PANSS) Symptom Architecture in Schizophrenia
Keane Lim,Oon-Him Peh,Zixu Yang,Gurpreet Rekhi,Attilio Rapisarda,Yuen-Mei See,Nur Amirah Abdul Rashid,Mei-San Ang,Sara-Ann Lee,Kang Sim,Hailiang Huang,Todd Lencz,Jimmy Lee,Max Lam,Max Lam +14 more
TL;DR: One of the largest transethnic factorial structures of PANSS symptom domains is reported, serving as crucial consolidation of a common metric PANSS that could aid in furthering the authors' understanding of schizophrenia.
Journal ArticleDOI
Long-term course of negative symptom subdomains and relationship with outcome in patients with a psychotic disorder
Annemarie P. M. Stiekema,Atiqul Islam,Edith J. Liemburg,Stynke Castelein,Edwin R. van den Heuvel,Jaap van Weeghel,André Aleman,Richard Bruggeman,Lisette van der Meer,GROUP-investigators +9 more
TL;DR: Lower symptom levels at baseline were related to better functioning (SA & ED) and quality of life (SA) at six years and low SA and low ED subgroups showed better outcomes than the other subgroups.
Journal ArticleDOI
Impact of positive emotion regulation training on negative symptoms and social functioning in schizophrenia: a field test
Jérôme Favrod,Alexandra Nguyen,A.M. Tronche,Olivier Blanc,Julien Dubreucq,Isabelle Chéreau-Boudet,Delphine Capdevielle,Pierre-Michel Llorca +7 more
TL;DR: This field test shows that participation in PEPS is accompanied by a reduction of negative symptoms and an improvement of social functioning, and both negative syndromes, reduction of expression and reduction of experience, are improved.
Journal ArticleDOI
Increased random exploration in schizophrenia is associated with inflammation
Flurin Cathomas,Flurin Cathomas,Federica Klaus,Federica Klaus,Karoline Guetter,Hui-Kuan Chung,Anjali Raja Beharelle,Tobias R Spiller,Rebecca Schlegel,Erich Seifritz,Matthias N. Hartmann-Riemer,Philippe N. Tobler,Stefan Kaiser +12 more
TL;DR: Low-grade inflammation in patients with SZ is associated with random exploration, which can be considered a behavioral marker for disorganization and a potential treatment target for maladaptive exploratory behaviors.
Journal ArticleDOI
Progress of negative symptoms over the initial 5 years of a first episode of psychosis.
Danyael Lutgens,Ridha Joober,Srividya N. Iyer,Martin Lepage,Ross Norman,Norbert Schmitz,Sally Mustafa,Sherezad Abadi,Ashok Malla +8 more
TL;DR: Negative symptoms improve significantly over the first 2 years of EI and subsequent amelioration was largely the result of expressivity, while Motivation deficits remained stable.
References
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
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Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
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Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
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