Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome.
Gregory P. Strauss,William P. Horan,Brian Kirkpatrick,Bernard A. Fischer,Bernard A. Fischer,William R. Keller,Pinar Miski,Robert W. Buchanan,Robert W. Buchanan,Michael F. Green,William T. Carpenter,William T. Carpenter +11 more
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TLDR
It is suggested that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-06-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Avolition & Apathy.read more
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Age-related deficits in intracortical myelination in young adults with bipolar disorder type I
Manpreet Sehmbi,Christopher D. Rowley,Luciano Minuzzi,Flávio Kapczinski,Jacek M. Kwiecien,Nicholas A. Bock,Benicio N. Frey +6 more
TL;DR: This foundational study is the first to show global age-related deficits in ICM maturation throughout the cortex in bipolar disorder, considering the impact of myelination on the maintenance of neural synchrony and the integrity of neural connections.
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Cannabis: A potential efficacious intervention for PTSD or simply snake oil?
TL;DR: There are indications that cannabis promotes cognitive disturbances, impairs neuronal plasticity and organization in the adolescent brain, promotes persistent functional brain changes, promotes abuse liability and, in highly vulnerable individuals, may exacerbate the course of schizophrenia.
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Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task
TL;DR: In this paper , the authors performed a coordinate-based meta-analysis, using the monetary incentive delay task, to identify which brain regions are implicated in different reward phases in functional magnetic resonance imaging in SZ.
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The development of a self-reported scale for measuring functionality in patients with schizophrenia--self-reported version of the graphic Personal and Social Performance (SRG-PSP) scale
Ya Mei Bai,Ya Mei Bai,Chih Yin Hsiao,Kao Chin Chen,Kai Lin Huang,Kai Lin Huang,I. Hui Lee,Ju Wei Hsu,Ju Wei Hsu,Po See Chen,Yen Kuang Yang +10 more
TL;DR: The SRG-PSP is a valid self-reported scale for the assessment of functionality in patients with schizophrenia and its correlations with psychiatric symptoms, daily life ability and quality of life are evaluated.
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Effort-based decision-making paradigms as objective measures of apathy in schizophrenia?
TL;DR: A clear consensus on clinical assessment instruments and paradigms seems to be critical for further progress in the field, and heterogeneity hampers comparability between studies and might partially explain divergent findings.
References
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Book
Cluster Analysis
TL;DR: This fourth edition of the highly successful Cluster Analysis represents a thorough revision of the third edition and covers new and developing areas such as classification likelihood and neural networks for clustering.
Book
Cluster analysis
TL;DR: Cluster analysis is a multivariate procedure for detecting natural groupings in data that resembles discriminant analysis in one respect—the researcher seeks to classify a set of objects into subgroups although neither the number nor members of the subgroups are known.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: Definition and Reliability
TL;DR: The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive.
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