Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials
TLDR
Resveratrol significantly improves glucose control and insulin sensitivity in persons with diabetes but does not affect glycemic measures in nondiabetic persons.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2013-08-01 and is currently open access. It has received 283 citations till now. The article focuses on the topics: Insulin resistance & Insulin.read more
Citations
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The effects of polyphenols and other bioactives on human health
TL;DR: Although deficiencies in polyphenol intake do not result in specific deficiency diseases, adequate intake of polyphenols could confer health benefits, especially with regard to chronic diseases, because tea, cocoa, fruits, and berries, as well as vegetables, are rich inpolyphenols.
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Polyphenols and Glycemic Control
TL;DR: Dietary polyphenols may inhibit α-amylase and α-glucosidase, inhibit glucose absorption in the intestine by sodium-dependent glucose transporter 1 (SGLT1), stimulate insulin secretion and reduce hepatic glucose output, and have anti-inflammatory effects.
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Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats.
Usune Etxeberria,Noemí Arias,Noemí Arias,Noemí Boqué,Maria Teresa Macarulla,Maria Teresa Macarulla,María P. Portillo,María P. Portillo,José Alfredo Martínez,José Alfredo Martínez,Fermín I. Milagro,Fermín I. Milagro +11 more
TL;DR: Overall, the administration of quercetin was found to be effective in lessening HFS-diet-induced gut microbiota dysbiosis and improving gut health.
Journal ArticleDOI
Resveratrol and Cardiovascular Diseases.
TL;DR: The discussions on potential beneficial effects of RES in CVDs should compare the results of preclinical studies with those of clinical trials, and difficulties in the interpretation of results arise from the use of high-dose RES supplements in research studies, whereas low RES concentrations are present in red wine.
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Health benefits of resveratrol: Evidence from clinical studies
Akhand Pratap Singh,Rachna Singh,Sumit Singh Verma,Vipin Rai,Catherine H. Kaschula,Pralay Maiti,Subash C. Gupta +6 more
TL;DR: The rapid metabolism and poor bioavailability have limited its therapeutic use, and the recently produced micronized resveratrol formulation called SRT501, shows promise.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Diagnosis and Classification of Diabetes Mellitus
TL;DR: The chronic hyperglycemia of diabetes is associated with long-term damage, dys-function, and failure of differentorgans, especially the eyes, kidneys, nerves, heart, and blood vessels.
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CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
TL;DR: The Consort 2010 Statement as discussed by the authors has been used worldwide to improve the reporting of randomised controlled trials and has been updated by Schulz et al. in 2010, based on new methodological evidence and accumulating experience.
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Global and societal implications of the diabetes epidemic
TL;DR: The prevention of diabetes and control of its micro- and macrovascular complications will require an integrated, international approach if the authors are to see significant reduction in the huge premature morbidity and mortality it causes.
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IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040.
Katherine Ogurtsova,J. D. da Rocha Fernandes,Yadi Huang,Ute Linnenkamp,Leonor Guariguata,Nam H. Cho,Nam H. Cho,David Cavan,Jonathan E. Shaw,Lydia Makaroff,Lydia Makaroff +10 more
TL;DR: Diabetes prevalence, deaths attributable to diabetes, and health expenditure due to diabetes continue to rise across the globe with important social, financial and health system implications.
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