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ESC guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Paulus Kirchhof, +3 more
- Vol. 70, Iss: 1, pp 1-84
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The article was published on 2017-01-01 and is currently open access. It has received 3603 citations till now. The article focuses on the topics: Management of atrial fibrillation.

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Citations
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Interventional occlusion of left atrial appendage in patients with atrial fibrillation. Acute and long-term outcome of occluder implantation in the LAARGE Registry.

TL;DR: LAARGE demonstrates a favorable outcome at 1-year follow-up in terms of stroke/TIA and major bleeding and is unique in its concept, as it is non-manufacturer sponsored and includes all commercially available devices.
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Inhibition of Small-Conductance Ca2+-Activated K+ Channels: The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?

TL;DR: Diness et al. as discussed by the authors showed that catheter ablation is more effective in maintaining normal sinus rhythm than antiarrhythmic drugs and is associated with a significant risk for adverse events.
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Trends in Prevalence of Non-Valvular Atrial Fibrillation and Anticoagulation Therapy in a Japanese Region ― Analysis Using the National Health Insurance Database ―

TL;DR: The prevalence of NVAF in subjects aged 40-74 years increased gradually from 2014 to 2017 and in the Tsugaru region in Japan, DOACs prescriptions increased and warfarin prescriptions decreased over the 4-year period.
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Stroke and Bleeding Risk Assessments in Patients With Atrial Fibrillation: Concepts and Controversies

TL;DR: There are a variety of clinical, electrical, biological, and genetic markers to guide stroke and bleeding risk assessments in AF and some have shown promise, but others remain less well-defined.
References
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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
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Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment

TL;DR: The TOAST stroke subtype classification system is easy to use and has good interobserver agreement and should allow investigators to report responses to treatment among important subgroups of patients with ischemic stroke.
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Spontaneous Initiation of Atrial Fibrillation by Ectopic Beats Originating in the Pulmonary Veins

TL;DR: The pulmonary veins are an important source of ectopic beats, initiating frequent paroxysms of atrial fibrillation and these foci respond to treatment with radio-frequency ablation.
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