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ESC guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Paulus Kirchhof, +3 more
- Vol. 70, Iss: 1, pp 1-84
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The article was published on 2017-01-01 and is currently open access. It has received 3603 citations till now. The article focuses on the topics: Management of atrial fibrillation.

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Citations
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Elevated heart rate and cardiovascular risk in hypertension

TL;DR: As most clinical guidelines now recommend the use of combination therapies in patients with hypertension, it might be desirable to consider as combination components drugs which lower HR, if HR is elevated such as, according to guideliines, when it is above 80 b/min.
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Poor Time in Therapeutic Range Control Is Associated With Adverse Clinical Outcomes in Patients With Non-Valvular Atrial Fibrillation: A Report From the Nationwide COOL-AF Registry

TL;DR: Poor TTR control is associated with adverse clinical outcomes in patients with NVAF who were on warfarin and efforts to ensure good TTR (≥65%) after initiation ofwarfarin are mandatory to minimize the risk of adverse clinical outcome.
Journal ArticleDOI

Non-vitamin K antagonist oral anticoagulants: impact of non-adherence and discontinuation.

TL;DR: Since there are several reasons for OAC underuse, future strategies to improve adherence should be implemented, that include more and better education about AF and stroke risk, as well as and specific information about the potential consequences of non-adherence to OAC.
References
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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI

Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment

TL;DR: The TOAST stroke subtype classification system is easy to use and has good interobserver agreement and should allow investigators to report responses to treatment among important subgroups of patients with ischemic stroke.
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Spontaneous Initiation of Atrial Fibrillation by Ectopic Beats Originating in the Pulmonary Veins

TL;DR: The pulmonary veins are an important source of ectopic beats, initiating frequent paroxysms of atrial fibrillation and these foci respond to treatment with radio-frequency ablation.
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