FAST slides : A novel surface for microarrays
TLDR
FAST slides have a much higher binding capacity for DNA and better spot-to-spot consistency than traditional poly-lysine-coated slides and are well suited for fluorescent detection because of their relatively low light scatter and efficient retention of arrayed DNA.Abstract:
We have evaluated FASTslides, a glass slide with a microporous polymeric surface that is a suitable substrate for microarray technology. The surface is a nitrocellulose-based polymer that binds DNA...read more
Citations
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DNA microarray technology: devices, systems, and applications.
TL;DR: This review covers applications of microarray devices and systems for pharmacogenomic research and drug discovery, infectious and genetic disease and cancer diagnostics, and forensic and genetic identification purposes.
Journal ArticleDOI
Chemical Strategies for Generating Protein Biochips
TL;DR: Different approaches using covalent and noncovalent chemistry are reviewed; particular emphasis is placed on the chemical specificity of protein attachment and on retention of protein function.
Journal ArticleDOI
Protein microarrays: meeting analytical challenges for clinical applications.
Lance A. Liotta,Virginia Espina,Arpita I. Mehta,Arpita I. Mehta,Valerie S. Calvert,Kevin P. Rosenblatt,David Geho,Peter J. Munson,Lynn Young,Julia Wulfkuhle,Emanuel F. Petricoin +10 more
TL;DR: Protein microarrays, one emerging class of proteomic technologies, have broad applications for discovery and quantitative analysis and is now employed for the analysis of biopsy samples in clinical trial research.
Journal ArticleDOI
Selective covalent protein immobilization: strategies and applications.
TL;DR: Prof. Micklefield?s research interests are at the chemistry?biology interface and include the redesign of nucleic acids, small-molecule control of gene expression, biosynthesis and biosynthetic engineering, nonribosomal peptides, biocatalysis, and enzyme mechanism.
Journal ArticleDOI
Progress in protein and antibody microarray technology.
TL;DR: This review aims to introduce these new technologies and highlights their current prospects and limitations for the screening of complex protein samples.
References
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