Journal ArticleDOI
Generation of Superoxide Radical during Autoxidation of Hydroxylamine and an Assay for Superoxide Dismutase
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TLDR
Hydrogen peroxide stimulated the autoxidation and superoxide dismutase inhibited the hydrogen peroxide-induced oxidation, results which suggest the participation of hydrogenperoxide in autoxidated and in the generation of superoxide radical.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1978-02-01. It has received 1480 citations till now. The article focuses on the topics: Autoxidation & Reactive oxygen species.read more
Citations
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Anthocyanin-Biofortified Colored Wheat Prevents High Fat Diet-Induced Alterations in Mice: Nutrigenomics Studies.
Saloni Sharma,Pragyanshu Khare,Ashok Kumar,Venkatesh Chunduri,Aman Kumar,Payal Kapoor,Priyanka Mangal,Kanthi Kiran Kondepudi,Mahendra Bishnoi,Monika Garg +9 more
TL;DR: The results suggest that the incorporation of colored wheat (especially black wheat) in the diet can prevent obesity and related metabolic complications.
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Astaxanthin attenuates oxidative stress and inflammatory responses in complete Freund-adjuvant-induced arthritis in rats
TL;DR: Oral administration of ATX exhibited significant anti-arthritic activity via enhancing the nociceptive threshold, reducing paw edema and improving arthritis scores, which could be attributed to its anti-inflammatory and antioxidant properties.
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Montelukast potentiates the protective effect of rofecoxib against kainic acid-induced cognitive dysfunction in rats
TL;DR: The present study emphasizes the positive modulation of cysteinyl leukotriene receptor inhibition on COX (cyclooxygenase) and LOX (lipoxygenases) pathways in the control of the neuroinflammation in kainic acid induced cognitive dysfunction in rats.
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Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model.
TL;DR: Evidence is provided that bergenin exerted protective effects in hyperoxaluria through mitochondrial protection that involves attenuation of oxidative stress and presented itself as an effective remedy in combating urolithiasis.
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Possible antioxidant and neuroprotective mechanisms of FK506 in attenuating haloperidol-induced orofacial dyskinesia.
TL;DR: FK506 could be a useful drug for the treatment of neuroleptic-induced orofacial dyskinesia after co-administration of FK506 dose dependently significantly reduced the lipid peroxidation and restored the decreased glutathione levels induced by chronic haloperidol treatment.
References
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Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
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The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase
Hara P. Misra,Irwin Fridovich +1 more
TL;DR: It is proposed that the autoxidation of epinephrine proceeds by at least two distinct pathways, only one of which is a free radical chain reaction involving O2- and hence inhibitable by superoxide dismutase.
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Inhibition of nitrite formation from hydroxylammoniumchloride: A simple assay for superoxide dismutase
Erich F. Elstner,Adelheid Heupel +1 more
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The Generation of Superoxide Radical during the Autoxidation of Hemoglobin
Hara P. Misra,Irwin Fridovich +1 more
TL;DR: Clostridial and spinach ferredoxins, reduced enzymatically by the action of ferredoxin-TPN+ oxidoreductase, have been shown to carry out the univalent reduction of oxygen.
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The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents.
Gerald Cohen,Richard E. Heikkila +1 more
TL;DR: The results point to a reaction between H2O2 and O2- (Haber-Weiss reaction) as a major source of the ·OH radicals and to a combined action of blocking ·OH formation as well as accelerating its removal.