Journal ArticleDOI
Generation of Superoxide Radical during Autoxidation of Hydroxylamine and an Assay for Superoxide Dismutase
Reads0
Chats0
TLDR
Hydrogen peroxide stimulated the autoxidation and superoxide dismutase inhibited the hydrogen peroxide-induced oxidation, results which suggest the participation of hydrogenperoxide in autoxidated and in the generation of superoxide radical.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1978-02-01. It has received 1480 citations till now. The article focuses on the topics: Autoxidation & Reactive oxygen species.read more
Citations
More filters
Journal ArticleDOI
Temporal changes in physiological and molecular markers in various brain regions following transient global ischemia in rats
TL;DR: The present study established the central role of BDNF and pro-inflammatory cytokines in the poststroke recovery and found the cortical and hippocampal regions were found to be more susceptible for ischemic injury.
Journal ArticleDOI
Protective effect of lutein supplementation on oxidative stress and inflammatory progression in cerebral cortex of streptozotocin-induced diabetes in rats
Amal J. Fatani,Mihir Y. Parmar,Hatem M. Abuohashish,Hatem M. Abuohashish,Mohamed M. Ahmed,Salem S. Al-Rejaie +5 more
TL;DR: It is suggested that lutein has the potential to ameliorate diabetes-induced oxidative and inflammatory damage and neural degeneration in the CCT.
Journal ArticleDOI
Protective effect of adenosine reuptake inhibitors in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes.
TL;DR: The major findings of the present study suggested that adenosine reuptake inhibitors dipyridamole and nimodipine could be a possible therapeutic option in neuroleptic induced TD.
Journal ArticleDOI
Neuroprotective effect of anethole against rotenone induced non-motor deficits and oxidative stress in rat model of Parkinson’s disease
Sadegh Moradi Vastegani,Seyed Esmaeil Khoshnam,E A Shah Mansouri,Somayeh Hajipour,Samireh Ghafouri,Nima Bakhtiari,Alireza Sarkaki,Yaghoob Farbood +7 more
TL;DR: In this paper , the authors investigated the possible neuroprotective effects of anethole as a potent antioxidant on rotenone-induced behavioral deficits, hippocampal neuronal death, and oxidative stress profile in rats.
Journal ArticleDOI
Design and synthesis of some acridine-piperazine hybrids for the improvement of cognitive dysfunction.
Anuradha Sharma,Poonam Piplani +1 more
TL;DR: A novel series of hybrid molecules was designed, synthesized and evaluated as multifunctional cholinesterase (ChE) inhibitors against cognitive dysfunction and found to be potential cognitive enhancers which were able to interfere with the scopolamine‐induced oxidative stress also.
References
More filters
Journal ArticleDOI
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
Journal ArticleDOI
The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase
Hara P. Misra,Irwin Fridovich +1 more
TL;DR: It is proposed that the autoxidation of epinephrine proceeds by at least two distinct pathways, only one of which is a free radical chain reaction involving O2- and hence inhibitable by superoxide dismutase.
Journal ArticleDOI
Inhibition of nitrite formation from hydroxylammoniumchloride: A simple assay for superoxide dismutase
Erich F. Elstner,Adelheid Heupel +1 more
Journal ArticleDOI
The Generation of Superoxide Radical during the Autoxidation of Hemoglobin
Hara P. Misra,Irwin Fridovich +1 more
TL;DR: Clostridial and spinach ferredoxins, reduced enzymatically by the action of ferredoxin-TPN+ oxidoreductase, have been shown to carry out the univalent reduction of oxygen.
Journal ArticleDOI
The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents.
Gerald Cohen,Richard E. Heikkila +1 more
TL;DR: The results point to a reaction between H2O2 and O2- (Haber-Weiss reaction) as a major source of the ·OH radicals and to a combined action of blocking ·OH formation as well as accelerating its removal.