Journal ArticleDOI
Generation of Superoxide Radical during Autoxidation of Hydroxylamine and an Assay for Superoxide Dismutase
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TLDR
Hydrogen peroxide stimulated the autoxidation and superoxide dismutase inhibited the hydrogen peroxide-induced oxidation, results which suggest the participation of hydrogenperoxide in autoxidated and in the generation of superoxide radical.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1978-02-01. It has received 1480 citations till now. The article focuses on the topics: Autoxidation & Reactive oxygen species.read more
Citations
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A mechanistic approach to explore the neuroprotective potential of zonisamide in seizures
TL;DR: The mechanisms behind the strong neuroprotective potential of zonisamide against seizures are demonstrated by attenuating the oxidative stress, inflammatory cascade and neuronal death associated with progression of seizures.
Journal ArticleDOI
Administration of Metabiotics Extracted From Probiotic Lactobacillus rhamnosus MD 14 Inhibit Experimental Colorectal Carcinogenesis by Targeting Wnt/β-Catenin Pathway.
Mridul Sharma,Geeta Shukla +1 more
TL;DR: It can be suggested that metabiotics modulate experimental colorectal cancer and could be used as a promising alternative of probiotics, particularly in immunocompromised individuals.
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Selenomethionine induces oxidative stress and modifies growth in rice (Oryza sativa L.) seedlings through effects on hormone biosynthesis and primary metabolism.
Rafael S. P. Malheiros,Fabrício C.M. Gonçalves,Fred A.L. Brito,Agustin Zsögön,Dimas M. Ribeiro +4 more
TL;DR: It is reported that SeMet increased concentrations of reactive oxygen species (ROS), inhibiting auxin and increasing ethylene production in rice seedlings, demonstrating a phytotoxic effect of SeMet for Rice seedlings and revealing a relationship between reactive oxygen Species, hormone homeostasis and carbon availability, which regulates growth responses.
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Understanding the role of 3-O-Acetyl-11-keto-β-boswellic acid in conditions of oxidative-stress mediated hepatic dysfunction during benzo(a)pyrene induced toxicity.
TL;DR: Interestingly, AK when supplemented to BaP treated animals ameliorated the above said biochemical indices appreciately, thus emphasing the protective potential of AK.
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Benincasa hispida alleviates amyloid pathology by inhibition of Keap1/Nrf2-axis: Emphasis on oxidative and inflammatory stress involved in Alzheimer's disease model.
TL;DR: In this paper, the effect of Benincasa hispida fruit extract in the Alzheimer's disease rats was investigated and the results indicated that the extract could be a possible neuroprotective alternative for Alzheimer's diseases.
References
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Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
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The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase
Hara P. Misra,Irwin Fridovich +1 more
TL;DR: It is proposed that the autoxidation of epinephrine proceeds by at least two distinct pathways, only one of which is a free radical chain reaction involving O2- and hence inhibitable by superoxide dismutase.
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Inhibition of nitrite formation from hydroxylammoniumchloride: A simple assay for superoxide dismutase
Erich F. Elstner,Adelheid Heupel +1 more
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The Generation of Superoxide Radical during the Autoxidation of Hemoglobin
Hara P. Misra,Irwin Fridovich +1 more
TL;DR: Clostridial and spinach ferredoxins, reduced enzymatically by the action of ferredoxin-TPN+ oxidoreductase, have been shown to carry out the univalent reduction of oxygen.
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The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents.
Gerald Cohen,Richard E. Heikkila +1 more
TL;DR: The results point to a reaction between H2O2 and O2- (Haber-Weiss reaction) as a major source of the ·OH radicals and to a combined action of blocking ·OH formation as well as accelerating its removal.