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Journal ArticleDOI

Generation of Superoxide Radical during Autoxidation of Hydroxylamine and an Assay for Superoxide Dismutase

Yasuhisa Kono
- 01 Feb 1978 - 
- Vol. 186, Iss: 1, pp 189-195
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TLDR
Hydrogen peroxide stimulated the autoxidation and superoxide dismutase inhibited the hydrogen peroxide-induced oxidation, results which suggest the participation of hydrogenperoxide in autoxidated and in the generation of superoxide radical.
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This article is published in Archives of Biochemistry and Biophysics.The article was published on 1978-02-01. It has received 1480 citations till now. The article focuses on the topics: Autoxidation & Reactive oxygen species.

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Citations
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Hydrogen sulfide attenuates hyperhomocysteinemia-induced mitochondrial dysfunctions in brain.

TL;DR: The findings suggest that H2S supplementation ameliorates Hcy-induced oxidative stress and mitochondrial dysfunctions suggesting it be a novel therapeutic to treat HHcy associated neurological disorders.
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Anti-hyperalgesic and anti-nociceptive potentials of standardized grape seed proanthocyanidin extract against CCI-induced neuropathic pain in rats.

TL;DR: GSPE showed a significant anti-hyperalgesic and anti-nociceptive effect in rats, and co-treatment of GSPE with morphine in CCI rats significantly reversed the morphine tolerance and enhanced its anti- Hyperalgesia effect as compared to the morphine-alone-treated group.
Journal ArticleDOI

Effect of trimethylgallic acid esters against chronic stress-induced anxiety-like behavior and oxidative stress in mice.

TL;DR: It is revealed that trimethylgallic acid esters could ameliorate chronic stress-induced various behavioral and biochemical alterations in mice, showing protective effects against chronic stress.
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Protective effect of nebivolol on reserpine-induced neurobehavioral and biochemical alterations in rats.

TL;DR: The results of the present study indicated that nebivolol has a protective role against reserpine-induced orofacial dyskinesia, indicating amelioration of oxidative stress in rat brains.
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Effect of Rhododendron arboreum Leaf Extract on the Antioxidant Defense System against Chromium (VI) Stress in Vigna radiata Plants.

TL;DR: It is observed that seed treatment with Rhododendron leaf extract resulted in the recuperation of seedling growth under chromium toxicity, and statistical analysis of the data with multiple linear regression supported that Rhododendedron leaf Extract can effectively ease chromium metal-induced phytotoxicity in Vigna radiata.
References
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Journal ArticleDOI

Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase

TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
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The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase

TL;DR: It is proposed that the autoxidation of epinephrine proceeds by at least two distinct pathways, only one of which is a free radical chain reaction involving O2- and hence inhibitable by superoxide dismutase.
Journal ArticleDOI

The Generation of Superoxide Radical during the Autoxidation of Hemoglobin

TL;DR: Clostridial and spinach ferredoxins, reduced enzymatically by the action of ferredoxin-TPN+ oxidoreductase, have been shown to carry out the univalent reduction of oxygen.
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The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents.

TL;DR: The results point to a reaction between H2O2 and O2- (Haber-Weiss reaction) as a major source of the ·OH radicals and to a combined action of blocking ·OH formation as well as accelerating its removal.
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