Journal ArticleDOI
Genome Mining-Driven Discovery of 5-Methylorsellinate-Derived Meroterpenoids from Aspergillus funiculosus.
Dexiu Yan,Yudai Matsuda +1 more
TLDR
In the fungus Aspergillus funiculosus CBS 11656 as discussed by the authors, the discovery of four new meroterpenoids (funiculolides A-D (1-4) derived from the aromatic polyketide 5-methylorsellinic acid (5-MOA) was reported.About:
This article is published in Organic Letters.The article was published on 2021-04-16. It has received 13 citations till now. The article focuses on the topics: Polyketide & Heterologous expression.read more
Citations
More filters
Journal ArticleDOI
Biocatalytic and chemical derivatization of fungal meroditerpenoid chevalone E
Zong-Hua Xiao,Jiayu Dong,Ao Li,Jiawang Dai,Yan-Ping Li,Qiu-Fen Hu,Li-Dong Shao,Yudai Matsuda,Wei-Guang Wang +8 more
TL;DR: This work has obtained meroditerpenoid chevalone E and its oxidized analogues by heterologously expressing these molecules in a solvent-free manner and confirmed their ability to adhere to polyene-like bonds.
Journal ArticleDOI
A Fungal Promiscuous UbiA Prenyltransferase Expands the Structural Diversity of Chrodrimanin-Type Meroterpenoids.
TL;DR: In this article , a UbiA-type prenyltransferase with substrate promiscuity was identified as the pivotal builder of the noncanonical chrodrimanin skeletons, which carry a benzo-cyclohexanone structure as the nonterpene part.
Journal ArticleDOI
Biosynthetic Elucidation and Structural Revision of Brevione E: Characterization of the Key Dioxygenase for Pathway Branching from Setosusin Biosynthesis
TL;DR: Brevione E (1) is a fungal hexacyclic meroditerpenoid with unique oxepane and cycloheptenone moieties, and its structure was examined in this paper .
References
More filters
Journal ArticleDOI
Easyfig: a genome comparison visualizer
TL;DR: Easyfig is a Python application for creating linear comparison figures of multiple genomic loci with an easy-to-use graphical user interface, enabling a rapid transition between analysis and the preparation of publication quality figures.
Journal ArticleDOI
Meroterpenoids produced by fungi
Regina Geris,Thomas J. Simpson +1 more
TL;DR: This review deals with the isolation and structure elucidation of meroterpenoids from higher and lower fungi, and discusses biosynthetic studies and biological activities as appropriate.
Journal ArticleDOI
Biosynthesis of fungal meroterpenoids
Yudai Matsuda,Ikuro Abe +1 more
TL;DR: This review summarizes the molecular bases for their biosyntheses, which were recently elucidated with modern techniques, and also discusses the plausible biosynthetic pathways of other related natural products lacking genetic information.
Journal ArticleDOI
1,n‐Hydrogen‐Atom Transfer (HAT) Reactions in Which n≠5: An Updated Inventory
TL;DR: The aim of this review is to draw up a comprehensive inventory of the less commonly encountered 1,n-radical translocations (n≠5) with the aim to update this topic with the most recent relevant data.
Journal ArticleDOI
Development of a novel quadruple auxotrophic host transformation system by argB gene disruption using adeA gene and exploiting adenine auxotrophy in Aspergillus oryzae
TL;DR: Results obtained showed that the adeA gene served as an efficient selection marker in developing a novel host-vector system with quadruple auxotrophy in A. oryzae, thus providing a powerful tool to breed multiple auxotrophic mutants from a deuteromycete wherein sexual crossing is impossible.