Gut Microbiota, Short-Chain Fatty Acids, and Herbal Medicines.
Wuwen Feng,Hui Ao,Cheng Peng +2 more
TLDR
Current knowledge aboutSCFAs origination, the role of SCFAs in health and disease, the influence of herbal medicine on SCF as production and the corresponding mechanisms are summarized.Abstract:
As an important source for traditional medical systems such as Ayurvedic medicine and traditional Chinese medicine, herbal medicines have received a lot of attention all over the world, especially in developing countries. Over the past decade, studies on gut microbiota have generated rich information for understanding how gut microbiota shape the functioning of our body system. In view of the importance of gut microbiota, the researchers engaged in studying herbal medicines have paid more and more attention to gut microbiota and gut microbiota metabolites. Of a variety of gut microbiota metabolites, short-chain fatty acids (SCFAs) have received most attention because of their important role in maintaining the hemostasis of hosts and recovery of diseases. Herbal medicines, as an important resource provider for production of SCFAs, have been demonstrated to be able to modulate gut microbiota composition and regulate SCFAs production. In this mini-review, we summarize current knowledge about SCFAs origination, the role of SCFAs in health and disease, the influence of herbal medicine on SCFAs production and the corresponding mechanisms. At the end of this review, the strategies and suggestions for further research of SCFAs and herbal medicines are also discussed.read more
Citations
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Gut microbiota, a new frontier to understand traditional Chinese medicines.
TL;DR: This review summarized the interactions between TCM and gut microbiota, and the pharmacological effects and features of metabolites produced during interactions betweenTCM and Gut microbiota, focusing on gut microbiota and metabolites.
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Relationship between gut microbiota and circulating metabolites in population-based cohorts
Dina Vojinovic,Djawad Radjabzadeh,Alexander Kurilshikov,Najaf Amin,Cisca Wijmenga,Lude Franke,M. Arfan Ikram,André G. Uitterlinden,Alexandra Zhernakova,Jingyuan Fu,Robert Kraaij,Cornelia M. van Duijn,Cornelia M. van Duijn +12 more
TL;DR: An in-depth study of the metabolome in two large population-based prospective cohorts is provided and 32 microbial traits associated with various metabolic biomarkers and specific lipoprotein subfractions are identified, providing insights into the role of microbiota in influencing host lipid levels.
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Neuroactive compounds in foods: Occurrence, mechanism and potential health effects.
TL;DR: This comprehensive review is to investigate the neuroactive compounds found naturally in foods or formed during fermentation, their formation pathways in humans, plants and microorganisms, potential health effects, effects of diet on the formation of microbial metabolites including neuro active compounds in the gut are discussed.
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Natural medicines for the treatment of fatigue: Bioactive components, pharmacology, and mechanisms.
Chuanhong Luo,Xiao-Rong Xu,Xi-Chuan Wei,Wuwen Feng,Hao-Zhou Huang,Hai-Yan Liu,Run-Chun Xu,Junzhi Lin,Li Han,Ding-Kun Zhang +9 more
TL;DR: In this paper, the authors outline the generation of fatigue and put emphasis on the anti-fatigue mechanism, bioactive components and clinic trials of natural medicines, which will contribute to the development of potential antifatigue agents and open up novel treatments for sub-health.
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Bioactive compounds produced by probiotics in food products
Bhawna Chugh,Afaf Kamal-Eldin +1 more
TL;DR: The health benefits of different bioactive compounds produced by probiotics, their mode of action and applications in food are focused on and viability of the microbial cells during processing, packaging, and storage of the food should be maintained in the foods supplemented with probiotics.
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