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Robert Kraaij

Researcher at Erasmus University Rotterdam

Publications -  90
Citations -  4276

Robert Kraaij is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Microbiome & Population. The author has an hindex of 26, co-authored 75 publications receiving 2853 citations. Previous affiliations of Robert Kraaij include University of Luxembourg & Erasmus University Medical Center.

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Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Hou-Feng Zheng, +174 more
- 01 Oct 2015 - 
TL;DR: Evidence is provided that low‐frequency non‐coding variants have large effects on BMD and fracture, thereby providing rationale for whole‐genome sequencing and improved imputation reference panels to study the genetic architecture of complex traits and disease in the general population.
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Quantifying prion disease penetrance using large population control cohorts

Eric Vallabh Minikel, +73 more
- 20 Jan 2016 - 
TL;DR: It is shown that missense variants in PRNP previously reported to be pathogenic are at least 30 times more common in the population than expected on the basis of genetic prion disease prevalence, a finding that supports the safety of therapeutic suppression of prion protein expression.
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Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene

J.M.J. Kremer, +11 more
- 01 Feb 1995 - 
TL;DR: It is concluded that a homozygous LH receptor gene mutation underlies the syndrome of autosomal recessive congenital Leydig cell hypoplasia in this family, and results have implications for the understanding of the development of the male genitalia.
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Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease

Laurie Robak, +13 more
- 01 Dec 2017 - 
TL;DR: It is suggested that multiple genetic hits may act in combination to degrade lysosomal function, enhancing Parkinson's disease susceptibility.
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Large-scale association analyses identify host factors influencing human gut microbiome composition

Alexander Kurilshikov, +109 more
- 18 Jan 2021 - 
TL;DR: In this article, the MiBioGen consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data from 18,340 individuals (24 cohorts) and found high variability across cohorts: only 9 of 410 genera were detected in more than 95% of samples.