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Open AccessJournal ArticleDOI

High-resolution Fourier-transform infrared chemical imaging with multiple synchrotron beams

TLDR
This advance allows truly diffraction-limited high-resolution imaging over the entire mid-infrared spectrum with high chemical sensitivity and fast acquisition speed while maintaining high-quality SNR.
Abstract
Conventional Fourier-transform infrared (FTIR) microspectroscopic systems are limited by an inevitable trade-off between spatial resolution, acquisition time, signal-to-noise ratio (SNR) and sample coverage. We present an FTIR imaging approach that substantially extends current capabilities by combining multiple synchrotron beams with wide-field detection. This advance allows truly diffraction-limited high-resolution imaging over the entire mid-infrared spectrum with high chemical sensitivity and fast acquisition speed while maintaining high-quality SNR.

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Proceedings ArticleDOI

Attenuated Total Reflection FTIR Microspectroscopy at the Australian Synchrotron

TL;DR: ATR FTIR microspectroscopy enables the analysis of samples with lateral resolution greater than is possible by transmission FTIR as mentioned in this paper, and has been developed for the study of materials with multilayer coatings and fine surface structures.
Journal ArticleDOI

Vibrational imaging for label-free cancer diagnosis and classification

TL;DR: A detailed overview of the major advances in the field of vibrational imaging for cancer diagnosis can be found in this paper, where the authors discuss the steps required to bring these powerful technologies from bench to bedside.
Journal ArticleDOI

Using mid infrared to perform investigations beyond the diffraction limits of microcristalline pathologies: advantages and limitation of Optical PhotoThermal IR spectroscopy

TL;DR: In this article , Fourier Transform InfraRed (FTIR) spectroscopy was used to determine the chemical composition of kidney stones as well as ectopic calcifications present in kidney biopsy.
Journal ArticleDOI

Biochemical profiling of rat embryonic stem cells grown on electrospun polyester fibers using synchrotron infrared microspectroscopy.

TL;DR: SIRMS studies can provide valuable insight into the early-stage response of NPCs to the morphology and surface chemistry of a biomaterial, and could therefore be a useful tool in the preparation and optimization of cellular scaffolds.
References
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BookDOI

Handbook of biological confocal microscopy

TL;DR: Methods for Three-Dimensional Imaging and Tutorial on Practical Confocal Microscopy and Use of the Confocal Test Specimen.
Journal ArticleDOI

Dirac charge dynamics in graphene by infrared spectroscopy

TL;DR: In this article, an infrared spectromicroscopy study of charge dynamics in graphene integrated in gated devices is presented, which reveals significant departures of the quasiparticle dynamics from predictions made for Dirac fermions in idealized, free-standing graphene.
Journal ArticleDOI

Near-field probing of vibrational absorption for chemical microscopy

TL;DR: In this article, the authors demonstrate the use of the apertureless approach to scan near field optical microscopy to obtain contrast in vibrational absorption on a scale of about 100 nanometres, about one-hundredth of a wavelength.
Journal ArticleDOI

Sea urchin spine calcite forms via a transient amorphous calcium carbonate phase.

TL;DR: It is shown that sea urchin spine regeneration proceeds via the initial deposition of amorphous calcium carbonate, which may have interesting implications for the development of sophisticated materials.
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