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Open AccessJournal ArticleDOI

High-resolution Fourier-transform infrared chemical imaging with multiple synchrotron beams

TLDR
This advance allows truly diffraction-limited high-resolution imaging over the entire mid-infrared spectrum with high chemical sensitivity and fast acquisition speed while maintaining high-quality SNR.
Abstract
Conventional Fourier-transform infrared (FTIR) microspectroscopic systems are limited by an inevitable trade-off between spatial resolution, acquisition time, signal-to-noise ratio (SNR) and sample coverage. We present an FTIR imaging approach that substantially extends current capabilities by combining multiple synchrotron beams with wide-field detection. This advance allows truly diffraction-limited high-resolution imaging over the entire mid-infrared spectrum with high chemical sensitivity and fast acquisition speed while maintaining high-quality SNR.

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Citations
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Journal ArticleDOI

Synchrotron-Based Infrared Spectral Imaging at the MIRIAM Beamline of Diamond Light Source

TL;DR: In this paper, the authors present a quantitative scientific technique for measuring both the molecular composition and its spatial distribution across large areas of materials using IR spectral imaging. Synchrotron radiatio...
Journal ArticleDOI

Polymeric microfluidic continuous flow mixer combined with hyperspectral FT-IR imaging for studying rapid biomolecular events.

TL;DR: The method uses an easy-to-fabricate microfluidic mixer platform integrated with hyperspectral FT-IR imaging for rapid acquisition of structural details and kinetic parameters of biomolecular reactions and successfully extracted kinetic and structural details of the conformational changes along the channel.
Journal ArticleDOI

Emerging technologies for biomedical analysis.

TL;DR: In this article, the most important original experimental platforms as well as current commercial approaches to biomedical analysis are critically chosen and reviewed, covering January 2010 to January 2014.
Journal ArticleDOI

Fast facial smile detection using convolutional neural network in an intelligent working environment

TL;DR: A fast facial smile detection algorithm with convolutional neural network and infrared imaging technology with spectral-spatial L1-norm constraint for low-resolution infrared spectrum that can recover a noise-free infrared spectrum.
Journal ArticleDOI

Compositional prior information in computed infrared spectroscopic imaging

TL;DR: A forward model for a sample with heterogeneities along the optical axis is presented and it is shown through simulation that the N-species constraint allows unambiguous inversion of Fourier transform interferometric data within the spatial frequency passband of the optical system.
References
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BookDOI

Handbook of biological confocal microscopy

TL;DR: Methods for Three-Dimensional Imaging and Tutorial on Practical Confocal Microscopy and Use of the Confocal Test Specimen.
Journal ArticleDOI

Dirac charge dynamics in graphene by infrared spectroscopy

TL;DR: In this article, an infrared spectromicroscopy study of charge dynamics in graphene integrated in gated devices is presented, which reveals significant departures of the quasiparticle dynamics from predictions made for Dirac fermions in idealized, free-standing graphene.
Journal ArticleDOI

Near-field probing of vibrational absorption for chemical microscopy

TL;DR: In this article, the authors demonstrate the use of the apertureless approach to scan near field optical microscopy to obtain contrast in vibrational absorption on a scale of about 100 nanometres, about one-hundredth of a wavelength.
Journal ArticleDOI

Sea urchin spine calcite forms via a transient amorphous calcium carbonate phase.

TL;DR: It is shown that sea urchin spine regeneration proceeds via the initial deposition of amorphous calcium carbonate, which may have interesting implications for the development of sophisticated materials.
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