Open AccessJournal Article
K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease
Shaul G. Massry,Jack W. Coburn,Glenn M. Chertow,Keith A. Hruska,Craig B. Langman,Hartmut H. Malluche,Kevin J. Martin,Linda McCann,James T. McCarthy,Sharon M. Moe,Isidro B. Salusky,Donald J. Sherrand,Miroslaw Smogorzewski,Kline Bolton,Charles Turkelson,Karyn A. Tappe,Stephen Tregear,James Reston,Wendy Bruening,Mark Monteforte,Janice Kaczmarek,Vivian Coates,George R. Bailie,Bryan N. Becker,Gavin J. Becker,Jerrilynn D. Burrowes,Fernando Carrera,David N. Churchill,Allan J. Collins,Peter W. Crooks,Dick DeZeeuw,Thomas A. Golper,Frank A. Gotch,Antonio M. Gotto,Roger Greenwood,Joel W. Greer,Richard H. Grimm,William E. Haley,Ronald J. Hogg,Alan R. Hull,Lawrence G. Hunsicker,Cynda Ann Johnson,Michael J. Klag,Saulo Klahr,Norbert Lameire,Francesco Locatelli,Sally McCulloch,Maureen Michael,Joseph V. Nally,John M. Newmann,Allen R. Nissenson,Keith C. Norris,Gregorio T. Obrador,William F. Owen,Thakor G. Patel,Glenda Payne,Claudio Ronco,Rosa A. Rivera-Mizzoni,Anton C. Schoolwerth,Robert A. Star,Michael W. Steffes,Theodore I. Steinman,John Pierre Wauters,Nanette K. Wenger,Josephine P. Briggs,Thomas H. Hostetter,Garabed Eknoyan,Aderra Levin,Nathan W. Levin,Sharon Andreoli,Sally Burrows-Hudson,Derrick Latos,Donna Mapes,Edith Oberley,Brian J.G. Pereira,Nadine Ferguson,Donna Fingerhut,Anthony Gucciardo,Margaret Klette,Doreen Mallard,Kerry Willis +80 more
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This article is published in American Journal of Kidney Diseases.The article was published on 2003-10-01 and is currently open access. It has received 2609 citations till now. The article focuses on the topics: Chronic kidney disease-mineral and bone disorder & Kidney disease.read more
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Oral treatment of metabolic acidosis in hemodialyzed patients and the implications on the hemodynamic status.
TL;DR: The findings emphasize the beneficial effects of correcting metabolic acidosis using the proposed treatment scheme with direct impact on hemodynamic status improvement.
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Fibroblast Growth Factor-23 Helps Explain the Biphasic Cardiovascular Effects of Vitamin D in Chronic Kidney Disease
TL;DR: The data presented in this review support the hypothesis that FGF-23 may be linked with the high cardiovascular risk in CKD through accelerating the onset of vascular calcification, secondary hyperparathyroidism, left ventricular hypertrophy and endothelial dysfunction.
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A randomized double-blind pilot study of serum phosphorus normalization in chronic kidney disease: a new paradigm for clinical outcomes studies in nephrology.
Geoffrey A. Block,Martha S. Persky,Markus Ketteler,Bryan Kestenbaum,Ravi Thadhani,Laura Kooienga,David Spiegel,John R. Asplin,James Ehrlich,Vincent Dennis,Allen R. Nissenson,Glenn M. Chertow,David C. Wheeler +12 more
TL;DR: It is fundamentally important for the nephrology community to critically evaluate the optimal serum phosphorus level in CKD and to conduct an adequately designed placebo-controlled randomized trial studying patient level outcomes.
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Denosumab for dialysis patients with osteoporosis: A cohort study.
Kyohei Kunizawa,Rikako Hiramatsu,Junichi Hoshino,Hiroki Mizuno,Yuko Ozawa,Akinari Sekine,Masahiro Kawada,Keiichi Sumida,Eiko Hasegawa,Masayuki Yamanouchi,Noriko Hayami,Tatsuya Suwabe,Naoki Sawa,Yoshifumi Ubara,Kenmei Takaichi +14 more
TL;DR: It is suggested that denosumab was equally as effective in HD as non-HD patients, however, careful hypocalcemia monitoring, for at least 4 weeks, is recommended for HD patients.
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Hyperparathyroidism in chronic kidney disease : a retrospective cohort study of costs and outcomes
TL;DR: It is suggested that iPTH levels beyond the targets suggested by clinical guidelines are associated with increased harm in patients with chronic kidney disease.
References
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Cinacalcet for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis
Geoffrey A. Block,Kevin J. Martin,Angel L.M. de Francisco,Stewart A. Turner,Morrell M. Avram,Michael Suranyi,Gavril Hercz,John Cunningham,Ali K. Abu-Alfa,Piergiorgio Messa,Daniel W. Coyne,Francesco Locatelli,Raphael M. Cohen,Pieter Evenepoel,Sharon M. Moe,Albert Fournier,Johann Braun,Laura C. McCary,Valter J. Zani,Kurt Olson,Tilman B. Drüeke,William G. Goodman +21 more
TL;DR: Cinacalcet lowers parathyroid hormone levels and improves calcium-phosphorus homeostasis in patients receiving hemodialysis who have uncontrolled secondary hyperparathyroidism.