Open AccessJournal Article
K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease
Shaul G. Massry,Jack W. Coburn,Glenn M. Chertow,Keith A. Hruska,Craig B. Langman,Hartmut H. Malluche,Kevin J. Martin,Linda McCann,James T. McCarthy,Sharon M. Moe,Isidro B. Salusky,Donald J. Sherrand,Miroslaw Smogorzewski,Kline Bolton,Charles Turkelson,Karyn A. Tappe,Stephen Tregear,James Reston,Wendy Bruening,Mark Monteforte,Janice Kaczmarek,Vivian Coates,George R. Bailie,Bryan N. Becker,Gavin J. Becker,Jerrilynn D. Burrowes,Fernando Carrera,David N. Churchill,Allan J. Collins,Peter W. Crooks,Dick DeZeeuw,Thomas A. Golper,Frank A. Gotch,Antonio M. Gotto,Roger Greenwood,Joel W. Greer,Richard H. Grimm,William E. Haley,Ronald J. Hogg,Alan R. Hull,Lawrence G. Hunsicker,Cynda Ann Johnson,Michael J. Klag,Saulo Klahr,Norbert Lameire,Francesco Locatelli,Sally McCulloch,Maureen Michael,Joseph V. Nally,John M. Newmann,Allen R. Nissenson,Keith C. Norris,Gregorio T. Obrador,William F. Owen,Thakor G. Patel,Glenda Payne,Claudio Ronco,Rosa A. Rivera-Mizzoni,Anton C. Schoolwerth,Robert A. Star,Michael W. Steffes,Theodore I. Steinman,John Pierre Wauters,Nanette K. Wenger,Josephine P. Briggs,Thomas H. Hostetter,Garabed Eknoyan,Aderra Levin,Nathan W. Levin,Sharon Andreoli,Sally Burrows-Hudson,Derrick Latos,Donna Mapes,Edith Oberley,Brian J.G. Pereira,Nadine Ferguson,Donna Fingerhut,Anthony Gucciardo,Margaret Klette,Doreen Mallard,Kerry Willis +80 more
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This article is published in American Journal of Kidney Diseases.The article was published on 2003-10-01 and is currently open access. It has received 2609 citations till now. The article focuses on the topics: Chronic kidney disease-mineral and bone disorder & Kidney disease.read more
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Journal ArticleDOI
Chronic Kidney Disease: Mineral and Bone Disorder in Children
TL;DR: Treatment of hyperphosphatemia and secondary hyperparathyroidism improves high-turnover bone disease but fails to correct defects in skeletal mineralization, and therapy must be titrated carefully to maintain optimal serum biochemical parameters according to stage of CKD.
Journal ArticleDOI
First- and second-generation immunometric PTH assays during treatment of hyperparathyroidism with cinacalcet HCl.
Kevin J. Martin,Harald Jüppner,Donald J. Sherrard,William G. Goodman,Mark R. Kaplan,George N. Nassar,Patricia Campbell,Mario Curzi,Chaim C. Harytan,Laura C. McCary,Matthew Guo,Stewart A. Turner,David A. Bushinsky +12 more
TL;DR: The data show that PTH can be monitored with either iPTH or biPTH assays during therapy with cinacalcet, and that cinacancet therapy does not exert a major influence on the ratio between PTH(1-84) and large, N-terminally truncated PTH fragments.
Journal ArticleDOI
Clinical and Practical Use of Calcimimetics in Dialysis Patients With Secondary Hyperparathyroidism.
Jordi Bover,Pablo Ureña,César Ruiz-García,Iara daSilva,Patricia Lescano,Jacqueline Del Carpio,José Ballarín,Mario Cozzolino +7 more
TL;DR: This review aims to summarize the results of studies on cinacalcet, up to and including the publication of the recent ADVANCE and EVOLVE RCTs, and to offer practical guidance on how to improve the clinical management of the most frequent adverse events associated with cinacanalyst, based on both currently available information and personal experience.
Journal ArticleDOI
Effects of parathyroid hormone on immune function.
Abdallah S. Geara,Mario R. Castellanos,Claude Bassil,Georgia Schuller-Levis,Eunkue Park,Marianne Smith,Michael Goldman,Suzanne El-Sayegh +7 more
TL;DR: Parathyroidectomy has been found to reverse the immunologic defect in patients with high PTH levels, but the clinical significance is unclear and further studies are needed to define if PTH does have immunomodulatory effects.
Journal ArticleDOI
Association between Serum Phosphate Levels and Stroke Risk in Patients Undergoing Hemodialysis: The Q-Cohort Study
Shunsuke Yamada,Kazuhiko Tsuruya,Masatomo Taniguchi,Masanori Tokumoto,Kiichiro Fujisaki,Hideki Hirakata,Satoru Fujimi,Takanari Kitazono +7 more
TL;DR: The results suggest the importance of managing serum phosphate levels within an appropriate range in hemodialysis patients, and suggest the need to select patients at a low risk of brain hemorrhage or infarction according to their serum phosphate level.
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Cinacalcet for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis
Geoffrey A. Block,Kevin J. Martin,Angel L.M. de Francisco,Stewart A. Turner,Morrell M. Avram,Michael Suranyi,Gavril Hercz,John Cunningham,Ali K. Abu-Alfa,Piergiorgio Messa,Daniel W. Coyne,Francesco Locatelli,Raphael M. Cohen,Pieter Evenepoel,Sharon M. Moe,Albert Fournier,Johann Braun,Laura C. McCary,Valter J. Zani,Kurt Olson,Tilman B. Drüeke,William G. Goodman +21 more
TL;DR: Cinacalcet lowers parathyroid hormone levels and improves calcium-phosphorus homeostasis in patients receiving hemodialysis who have uncontrolled secondary hyperparathyroidism.