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Journal ArticleDOI

Mechanical properties and the hierarchical structure of bone

TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.
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This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.

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Bioinspired Concentric-Cylindrical Multilayered Scaffolds with Controllable Architectures: Facile Preparation and Biological Applications.

TL;DR: Considering the facile preparation process and versatile applications, this study will open up a new pathway to fabricate scaffolds with controllable architectures and expand their biodegradable polymer applications.

Characterization of Bone Material Properties and Microstructure in Osteogenesis Imperfecta/Brittle Bone Disease

John Jameson
TL;DR: There was a strong negative correlation between the elevated vascular porosity of OI cortical bone and its elastic modulus, flexural yield strength, and ultimate strength and a deep connection between bone structure and mechanical integrity at multiple length scales.
Journal ArticleDOI

Quantification of stiffness measurement errors in resonant ultrasound spectroscopy of human cortical bone

TL;DR: This work was motivated by the need to quantify the errors on stiffness constants due to different error sources in RUS, including uncertainties on the resonant frequencies and specimen dimensions and imperfect rectangular parallelepiped (RP) specimen geometry.
Journal ArticleDOI

Deep learning approach to assess damage mechanics of bone tissue

TL;DR: In this paper, the classification and prediction of mechanical states of cortical and trabecular bone tissue using convolutional neural networks (CNNs), residual neural network (ResNet), and transfer learning applied to a novel dataset derived from high-resolution synchrotron-radiation micro-computed tomography (SR-microCT) images acquired in uniaxial continuous compression in situ.
Journal ArticleDOI

Effects of hydrofluoric acid and anodised micro and micro/nano surface implants on early osseointegration in rats

TL;DR: Data indicate that the hierarchical hybrid micro/nano surface of the implant can promote osseointegration in the earliest stage of implantation, and may be a promising option for further clinical use.
References
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Journal ArticleDOI

The compressive behavior of bone as a two-phase porous structure.

TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
Journal ArticleDOI

Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.

TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
Journal ArticleDOI

The mechanical behaviour of cancellous bone

TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
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Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation

TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.
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