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Journal ArticleDOI

Mechanical properties and the hierarchical structure of bone

TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.
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This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.

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Journal ArticleDOI

A hierarchically designed nanocomposite hydrogel with multisensory capabilities towards wearable devices for human-body motion and glucose concentration detection

TL;DR: In this article, the authors proposed a novel strategy for the development of hybrid hydrogel nanocomposites for sensing human-body motion and glucose level in sweat, which comprises of a semi-interpenetrating polymer network where the nanometric level of hierarchy enables high conductivity, while the microscopic level imparts favorable electrochemical and mechanical properties.
Journal ArticleDOI

Ductility and brittleness of bone

TL;DR: In this article, the existence of screw dislocations parallel to the collagen molecules with a Burger's vector of 1 nm length is postulated, and deformation occurs by thermally activated kink pair formation in these defects.
Journal ArticleDOI

A Fluidic Culture Platform for Spatially Patterned Cell Growth, Differentiation, and Cocultures.

TL;DR: This work develops a three-dimension representation of the cell phenotype in stem cell cultures within perfusion bioreactors that shows the similarity to native tissues and consequently cell phenotype.
Book ChapterDOI

Extracellular Matrix and Tissue Regeneration

TL;DR: Extracellular matrix (ECM) is a complex interlinked composite of collagenous molecules, non-collagenous molecules and water-rich mucopolysaccharide ground substance as discussed by the authors.
Journal ArticleDOI

Properties and Performance of Ultrafine Grained Titanium for Biomedical Applications

TL;DR: The overall improvements in microstructure provided by ECAP technique coupled with surface etching resulted in a remarkable performance of cpTi alloy for biomedical applications.
References
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Journal ArticleDOI

The compressive behavior of bone as a two-phase porous structure.

TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
Journal ArticleDOI

Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.

TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
Journal ArticleDOI

The mechanical behaviour of cancellous bone

TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
Journal ArticleDOI

Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation

TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.
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