Journal ArticleDOI
Mechanical properties and the hierarchical structure of bone
TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.About:
This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.read more
Citations
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Biomimetic and mesoporous nano-hydroxyapatite for bone tissue application: a short review.
Giulia Molino,Maria Chiara Palmieri,Giorgia Montalbano,Sonia Lucia Fiorilli,Chiara Vitale-Brovarone +4 more
TL;DR: This review aims to summarise and critically analyse the most used methods to prepare physiologic-like nano-HA, in the form of plates or rods, similar to the HA present in the human bones, with physiological-like morphology.
Journal ArticleDOI
Hydroxyapatite formation on sol-gel derived poly(ε-caprolactone)/bioactive glass hybrid biomaterials.
TL;DR: Cell viability within the different PCL/BG hybrid samples appeared to be influenced by compositional differences whereby higher PCL contents correlated with slight reduction in cell viability, and cytotoxic effects of PCL-BG hybrids prepared by the sol-gel process using a tertiary glass composition may have considerable potential for bone tissue regeneration applications.
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Strategies for Bone Regeneration: From Graft to Tissue Engineering
Giulia Battafarano,Michela Rossi,Viviana De Martino,Francesco Marampon,Luca Borro,Aurelio Secinaro,Andrea Del Fattore +6 more
TL;DR: In this article, a review of the options available for bone regeneration, focusing on tissue engineering strategies based on the use of different biomaterials combined with cells and growth factors, is presented.
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Nano-structural, compositional and micro-architectural signs of cortical bone fragility at the superolateral femoral neck in elderly hip fracture patients vs. healthy aged controls.
Petar Milovanovic,Petar Milovanovic,Zlatko Rakočević,Danijela Djonic,Vladimir Zivkovic,Michael Hahn,Slobodan Nikolić,Michael Amling,Bjoern Busse,Marija Djuric +9 more
TL;DR: Along with increased crystal size, a shift towards higher mineralization and a tendency to increased cortical porosity and reduced osteocyte lacunar number delineate that cortical bone of the superolateral femoral neck bears distinct signs of fragility at various levels of its structural organization.
Journal ArticleDOI
A comparative study of young and mature bovine cortical bone.
TL;DR: Optical microscopy revealed that mature bone has a more established and less porous microstructure compared to young bone, and mature untreated bone was found to be stronger in both directions for the untreated and deproteinized cases.
References
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Journal ArticleDOI
The compressive behavior of bone as a two-phase porous structure.
Dennis R. Carter,Wilson C. Hayes +1 more
TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
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Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.
TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
Journal ArticleDOI
The mechanical behaviour of cancellous bone
TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
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Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation
TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.