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Journal ArticleDOI

Mechanical properties and the hierarchical structure of bone

TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.
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This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.

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Mesoporous bioactive glasses: mechanical reinforcement by means of a biomimetic process.

TL;DR: This work presents for the first time a new property of MBGs: the mechanical reinforcement of a bioactive glass through a biomimetic process, explained in terms of the outstanding bioactive behavior and the three-dimensional mesoporous structure that is exclusive for this bioceramics family.
Journal ArticleDOI

New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties

TL;DR: Characterizing TCDD-induced modulations of bone tissue, and the role of AHR in dioxin-induced bone toxicity and for normal bone phenotype, results in harder bone matrix, thinner cortical bone, mechanically weaker bones and most notably, increased trabecular bone volume fraction in Ahr(+/+) mice.
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Effects of compaction pressure and particle shape on the porosity and compression mechanical properties of sintered Ti6Al4V powder compacts for hard tissue implantation

TL;DR: Results have shown that yield strength of the powder compacts of 40-42% porosity was comparable with that of human cortical bone, and Ti6Al4V Powder compacts showed higher strength at similar porosity range.
Journal ArticleDOI

Shell-core bi-layered scaffolds for engineering of vascularized osteon-like structures.

TL;DR: These shell-core bi-layered scaffolds with porous, coil-like shell and nanofibrous tubular cores represent a new scaffolding technology base for the creation of osteon analogs.
Journal ArticleDOI

Bioactive Calcium Phosphate-Based Composites for Bone Regeneration

TL;DR: The present work provides an overview about the reported strategies to develop and optimize bioceramics, while also highlighting future perspectives in the development of bioactive ceramic composites for bone tissue regeneration.
References
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Journal ArticleDOI

The compressive behavior of bone as a two-phase porous structure.

TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
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Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.

TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
Journal ArticleDOI

The mechanical behaviour of cancellous bone

TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
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Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation

TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.
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