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Journal ArticleDOI

Mechanical properties and the hierarchical structure of bone

TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.
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This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.

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Nanostructured Polymeric Scaffolds for Orthopaedic Regenerative Engineering

TL;DR: This review provides the fundamental guidelines for the design and development of nanostructured scaffolds for the regeneration of various tissue types in human upper and lower extremities such as skin, ligament, tendon, and bone.
Journal ArticleDOI

Investigation of the three-dimensional orientation of mineralized collagen fibrils in human lamellar bone using synchrotron X-ray phase nano-tomography.

TL;DR: 3-D organization of mineralized collagen fibrils in human cortical bone based on synchrotron X-ray phase nano-tomography images improves the understanding of the lamellar arrangement in bone and allow more detailed investigations of structure-function relationships at this scale, providing templates for bio-inspired materials.
Journal ArticleDOI

Citrate-Based Biomaterials and Their Applications in Regenerative Engineering

TL;DR: Fundamental design considerations, strategies to incorporate unique functionality, and examples of how citrate-based biomaterials can be an enabling technology for regenerative engineering are discussed.
Journal ArticleDOI

Velocity dispersion of guided waves propagating in a free gradient elastic plate: Application to cortical bone

TL;DR: In this study, the simplest form of gradient theory is used to theoretically determine the velocity dispersion curves of guided modes propagating in isotropic bone-mimicking plates and results indicate that gradient elasticity can provide supplementary information to better understand guided waves in bones.
Journal ArticleDOI

Mechanical properties of hierarchical lattices

TL;DR: In this article, the stiffness and strength of lattices with multiple hierarchical levels of structural hierarchy was examined. But the results of the analysis were limited to two-dimensional and three-dimensional lattices.
References
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Journal ArticleDOI

The compressive behavior of bone as a two-phase porous structure.

TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
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Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.

TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
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The mechanical behaviour of cancellous bone

TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
Journal ArticleDOI

Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation

TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.
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