Journal ArticleDOI
Mechanical properties and the hierarchical structure of bone
TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.About:
This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.read more
Citations
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Journal ArticleDOI
Materials evolution of bone plates for internal fixation of bone fractures: A review
TL;DR: In this paper, the authors reviewed the development of implant design and biomaterials for bone plates and discussed recent development of hybrid bone plates that contain bioactive elements or factors for fracture healing enhancement.
Journal ArticleDOI
Surface delivery of tunable doses of BMP-2 from an adaptable polymeric scaffold induces volumetric bone regeneration
M. Bouyer,Raphael Guillot,Jonathan Lavaud,Cedric Plettinx,Cécile Olivier,Véronique Curry,Jean Boutonnat,Jean-Luc Coll,Françoise Peyrin,Véronique Josserand,Georges Bettega,Catherine Picart +11 more
TL;DR: This work presents a novel means for repairing a critical size volumetric bone femoral defect in the rat by combining a osteoinductive surface coating (2D) to a polymeric scaffold (3D hollow tube) made of commercially-available PLGA.
Journal ArticleDOI
Bioactive and biodegradable nanocomposites and hybrid biomaterials for bone regeneration
TL;DR: The current state of bioactive and biodegradable nanocomposite and O/I hybrid biomaterials and their applications in bone regeneration are reviewed and a perspective on the future application is concluded.
Book ChapterDOI
Biomimetic Porous Titanium Scaffolds for Orthopedic and Dental Applications
TL;DR: In this paper, a review on the characteristics of porous metal scaffolds used as bone replacement as well as fabrication processes of porous titanium (Ti) scaffolds through a space holder sintering method is presented.
Journal ArticleDOI
Hierarchical Modeling of the Elastic Properties of Bone at Submicron Scales: The Role of Extrafibrillar Mineralization
Svetoslav Nikolov,Dierk Raabe +1 more
TL;DR: It is shown that the extrafibrillar mineralization considerably reinforces the fibrils' mechanical properties in the transverse directions and the fibils' shear moduli.
References
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Journal ArticleDOI
The compressive behavior of bone as a two-phase porous structure.
Dennis R. Carter,Wilson C. Hayes +1 more
TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
Journal ArticleDOI
Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.
TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
Journal ArticleDOI
The mechanical behaviour of cancellous bone
TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
Journal ArticleDOI
Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation
TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.