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Journal ArticleDOI

Mechanical properties and the hierarchical structure of bone

TLDR
Further investigations of mechanical properties at the "materials level", in addition to the studies at the 'structural level' are needed to fill the gap in present knowledge and to achieve a complete understanding of the mechanical properties of bone.
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This article is published in Medical Engineering & Physics.The article was published on 1998-03-01. It has received 2352 citations till now.

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Tissue Engineering for the Insertions of Tendons and Ligaments: An Overview of Electrospun Biomaterials and Structures.

TL;DR: In this article, a review of the most relevant studies that applied electrospinning to produce scaffolds for the regeneration of the enthesis and the myotendinous junction, giving a comprehensive overview on the progress made in the field, in particular focusing on the electro-spinning strategies to produce these scaffolds and their mechanical, in vitro and in vivo outcomes.
Journal ArticleDOI

Low temperature aqueous precipitation of needle-like nanophase hydroxyapatite

TL;DR: A comparison and characterisation of hydroxyapatite (HA), a popular calcium phosphate (CaP) biomaterial, synthesised by an aqueous precipitation (AP) method, found initial pH was found to influence the crystallisation process and determine the CaP phase formed as well as the resultant particle and crystallite sizes.
Journal ArticleDOI

Nanoengineered biocomposite tricomponent polymer based matrices for bone tissue engineering

TL;DR: In this paper, the main objective of the study was to create biocomposite nanostructured scaffolds by incorporating collagen and HA nanoparticles into poly(L-lactic acid)-co-poly(ϵ-caprolactone) by electrospinning.
Journal ArticleDOI

Finite element 3D modeling of mechanical behavior of mineralized collagen microfibrils

TL;DR: An equivalent homogenized model was developed to assess the whole microfibril mechanical properties under varying mechanical properties of each phase, and equivalent Young's modulus and Poisson's ratio were obtained under tensile load with symmetric and periodic boundary conditions.
Journal ArticleDOI

Fabrication and characterization of electrospun osteon mimicking scaffolds for bone tissue engineering

TL;DR: The aim of this study was to develop a technique to fabricate scaffolds that mimic the organization of an osteon, the structural unit of cortical bone.
References
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Journal ArticleDOI

The compressive behavior of bone as a two-phase porous structure.

TL;DR: These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
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Young's modulus of trabecular and cortical bone material: ultrasonic and microtensile measurements.

TL;DR: The results suggest that when considered mechanically, cortical and trabecular bone are not the same material.
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The mechanical behaviour of cancellous bone

TL;DR: The results of this previous study are applied to cancellous bone in an attempt to further understand its mechanical behaviour and the results agree reasonably well with experimental data available in the literature.
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Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation

TL;DR: An experimental investigation was undertaken to measure the intrinsic elastic properties of several of the microstructural components of human vertebral trabecular bone and tibial cortical bone by the nanoindentation method, and differences in the measured moduli are statistically significant.
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