Journal ArticleDOI
Medicinal plants used in the treatment of tuberculosis - Ethnobotanical and ethnopharmacological approaches.
Javad Sharifi-Rad,Bahare Salehi,Zorica Stojanović-Radić,Patrick Valere Tsouh Fokou,M. Sharifi-Rad,Gail B. Mahady,Majid Sharifi-Rad,Mohammad Reza Masjedi,Temitope O. Lawal,Seyed Abdulmajid Ayatollahi,Javid Masjedi,Razieh Sharifi-Rad,William N. Setzer,Mehdi Sharifi-Rad,Farzad Kobarfard,Atta-ur Rahman,Muhammad Iqbal Choudhary,Athar Ata,Marcello Iriti +18 more
TLDR
The validation of their efficacy and safety as antituberculosis agents is far from being reached, and, therefore, according to an evidence-based approach, more high-level randomized clinical trials are urgently needed.About:
This article is published in Biotechnology Advances.The article was published on 2017-07-08. It has received 69 citations till now. The article focuses on the topics: Tuberculosis & Population.read more
Citations
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Journal ArticleDOI
Carvacrol and human health: A comprehensive review.
Mehdi Sharifi-Rad,Elena Maria Varoni,Marcello Iriti,Miquel Martorell,William N. Setzer,María del Mar Contreras,Bahare Salehi,Azam Soltani-Nejad,Sadegh Rajabi,Mercedeh Tajbakhsh,Javad Sharifi-Rad,Javad Sharifi-Rad +11 more
TL;DR: The present review illustrates the state‐of‐the‐art studies on the antimicrobial, antioxidant, and anticancer properties of CV.
Journal ArticleDOI
Thymol, thyme, and other plant sources: Health and potential uses
Bahare Salehi,Abhay Prakash Mishra,Ila Shukla,Mehdi Sharifi-Rad,María del Mar Contreras,Antonio Segura-Carretero,Hannane Fathi,Nafiseh Nasri Nasrabadi,Farzad Kobarfard,Javad Sharifi-Rad,Javad Sharifi-Rad +10 more
TL;DR: Thymol exhibits antimicrobial, antioxidant, anticarcinogenesis, anti‐inflammatory, and antispasmodic activities, as well as a potential as a growth enhancer and immunomodulator; these bioactivities have been covered.
Journal ArticleDOI
Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy
Mehdi Sharifi-Rad,Elena Maria Varoni,Bahare Salehi,Javad Sharifi-Rad,Javad Sharifi-Rad,Karl R. Matthews,Seyed Abdulmajid Ayatollahi,Seyed Abdulmajid Ayatollahi,Farzad Kobarfard,Salam A. Ibrahim,Dima Mnayer,Zainul Amiruddin Zakaria,Zainul Amiruddin Zakaria,Majid Sharifi-Rad,Zubaida Yousaf,Marcello Iriti,Adriana Basile,Daniela Rigano +17 more
TL;DR: A literature overview on Zingiber spp.
Journal ArticleDOI
Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion.
Mehdi Sharifi-Rad,Patrick Valere Tsouh Fokou,Farukh Sharopov,Miquel Martorell,Adedayo O. Ademiluyi,Jovana Rajkovic,Bahare Salehi,Natália Martins,Marcello Iriti,Javad Sharifi-Rad,Javad Sharifi-Rad +10 more
TL;DR: From traditional uses as herbal remedies to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential, comprehensively reviewed the plant sources used as antiulcers agents.
Journal ArticleDOI
Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.
Bahare Salehi,Nanjangud V. Anil Kumar,Bilge Sener,Mehdi Sharifi-Rad,Mehtap Kilic,Gail B. Mahady,Sanja Vlaisavljevic,Marcello Iriti,Farzad Kobarfard,William N. Setzer,Seyed Abdulmajid Ayatollahi,Seyed Abdulmajid Ayatollahi,Athar Ata,Javad Sharifi-Rad,Javad Sharifi-Rad +14 more
TL;DR: A survey of plants that have shown anti-HIV activity, both in vitro and in vivo is presented, to provide therapeutic options for populations with limited resources or access to currently efficacious chemotherapies.
References
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Book
Indian Medicinal Plants
TL;DR: Indian medicinal plants/, Indian medicinal plants /, مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی
Journal ArticleDOI
Natural Products as Sources of New Drugs over the Last 25 Years
David J. Newman,Gordon M. Cragg +1 more
TL;DR: This review is an updated and expanded version of two prior reviews that were published in this journal in 1997 and 2003 and is able to identify only one de novo combinatorial compound approved as a drug in this 25 plus year time frame.
Journal ArticleDOI
Natural products: a continuing source of novel drug leads.
Gordon M. Cragg,David J. Newman +1 more
TL;DR: This review traces natural products drug discovery, outlining important drugs from natural sources that revolutionized treatment of serious diseases and effective drug development depends on multidisciplinary collaborations.
Journal ArticleDOI
A new antibiotic kills pathogens without detectable resistance
Losee Lucy Ling,Tanja Schneider,Aaron J. Peoples,Amy Spoering,Ina Engels,Brian P. Conlon,A. Mueller,Till F. Schäberle,Dallas Hughes,Slava S. Epstein,M. Jones,Linos Lazarides,Victoria Alexandra Steadman,Cohen Dr,Cintia R. Felix,Fetterman Ka,William Millett,Anthony Nitti,Ashley Zullo,Chao Chen,Kim Lewis +20 more
TL;DR: The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance, as well as several methods to grow uncultured organisms by cultivation in situ or by using specific growth factors.
Journal ArticleDOI
Discovery and resupply of pharmacologically active plant-derived natural products: A review.
Atanas G. Atanasov,Birgit Waltenberger,Eva-Maria Pferschy-Wenzig,Thomas Linder,Christoph Wawrosch,Pavel Uhrin,Veronika Temml,Limei Wang,Stefan Schwaiger,Elke H. Heiss,Judith M. Rollinger,Judith M. Rollinger,Daniela Schuster,Johannes M. Breuss,Valery N. Bochkov,Marko D. Mihovilovic,Brigitte Kopp,Rudolf Bauer,Verena M. Dirsch,Hermann Stuppner +19 more
TL;DR: While the intrinsic complexity of natural product-based drug discovery necessitates highly integrated interdisciplinary approaches, the reviewed scientific developments, recent technological advances, and research trends clearly indicate that natural products will be among the most important sources of new drugs in the future.
Related Papers (5)
Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy
Mehdi Sharifi-Rad,Elena Maria Varoni,Bahare Salehi,Javad Sharifi-Rad,Javad Sharifi-Rad,Karl R. Matthews,Seyed Abdulmajid Ayatollahi,Seyed Abdulmajid Ayatollahi,Farzad Kobarfard,Salam A. Ibrahim,Dima Mnayer,Zainul Amiruddin Zakaria,Zainul Amiruddin Zakaria,Majid Sharifi-Rad,Zubaida Yousaf,Marcello Iriti,Adriana Basile,Daniela Rigano +17 more