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Open AccessJournal ArticleDOI

Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects

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TLDR
In this paper, the most important mechanisms of generation and transport of the key species in the plasmas of atmospheric-pressure plasma jets and other non-equilibrium atmospheric pressure plasms are introduced and examined from the viewpoint of their applications in plasma hygiene and medicine and other relevant fields.
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This article is published in Physics Reports.The article was published on 2016-05-04 and is currently open access. It has received 825 citations till now.

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Plasma-induced selectivity in bone cancer cells death.

TL;DR: The plasma treatment unveiled effective lethal and selective action towards osteosarcoma cells and healthy cells remain fully viable and unaffected by the treatment, opening new pathways for treatment of metastatic bone disease with a minimally invasive approach.
Journal ArticleDOI

The effect of liquid target on a nonthermal plasma jet - Imaging, electric fields, visualization of gas flow and optical emission spectroscopy

TL;DR: In this paper, the authors describe the complex study of the interaction of a helium plasma jet with distilled water and saline, and the discharge development, spatial distribution of the excited species, electric field measurement results and the results of the Schlieren imaging are presented.
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Effects of •OH and •NO radicals in the aqueous phase on H2O2 and generated in plasma-activated medium

TL;DR: In this article, the role of hydroxyl radicals and nitric oxide in the generation of reactive oxygen nitrogen species in a culture medium irradiated with cold atmospheric plasmas or non-equilibrium atmospheric pressure plasma was investigated.
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On the penetration depth of reactive oxygen and nitrogen species generated by a plasma jet through real biological tissue

TL;DR: It is found that the reactive oxygen species (ROS) produced by the plasma are significantly consumed by the tissue and under certain experimental conditions, some of the RONS can penetrate through 1.25 mm of the biological tissue.
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The selective effect of plasma activated medium in an in vitro co-culture of liver cancer and normal cells

TL;DR: By using the co-culture system, it is found that there is an optimum dose of PAM to induce significant cancer cell apoptosis while keeping minimum damage to normal cells.
References
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Journal ArticleDOI

Superoxide Dismutase AN ENZYMIC FUNCTION FOR ERYTHROCUPREIN (HEMOCUPREIN)

TL;DR: The demonstration that O2·- can reduce ferricytochrome c and tetranitromethane, and that superoxide dismutase, by competing for the superoxide radicals, can markedly inhibit these reactions, is demonstrated.
Journal ArticleDOI

Free Radicals in the Physiological Control of Cell Function

Wulf Dröge
TL;DR: There is growing evidence that aging involves, in addition, progressive changes in free radical-mediated regulatory processes that result in altered gene expression.
Journal ArticleDOI

Nitric Oxide and Peroxynitrite in Health and Disease

TL;DR: Current evidence indicates that most of the cytotoxicity attributed to NO is rather due to peroxynitrite, produced from the diffusion-controlled reaction between NO and another free radical, the superoxide anion, which is presented in detail in this review.
Journal ArticleDOI

Photodynamic therapy for cancer

TL;DR: PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin.
Book

Photodynamic Therapy

C.J. Gomer
TL;DR: A comprehensive review of mechanisms of subcellular and tumor localization of photosensitizing agents, as well as of molecular, cellular, and tumor responses associated with photodynamic therapy, are discussed.
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