Journal ArticleDOI
Recent advancement of gelatin nanoparticles in drug and vaccine delivery.
TLDR
The current review highlights the different formulation aspects of gelatin nanoparticles which affect the particle characteristics like zeta potential, polydispersity index, entrapment efficacy and drug release properties and gives emphasis on the major applications of collagen nanoparticles in drug and vaccine delivery, gene delivery to target tissues and nutraceutical delivery for improving the poor bioavailabity of bioactive phytonutrients.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2015-11-01. It has received 176 citations till now. The article focuses on the topics: Drug delivery & Targeted drug delivery.read more
Citations
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Book ChapterDOI
Nanotechnology Approaches for Increasing Nutrient Bioavailability.
TL;DR: This chapter focuses on the utilization of food-grade nanoparticles for improving the performance of nutraceuticals in functional foods and beverages.
Journal ArticleDOI
Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy.
TL;DR: This review summarized source materials and procedures that have been used for constructing and characterizing biomimetic nanoparticles with a focus on their application in cancer therapy.
Journal ArticleDOI
Protein-Based Nanoparticles as Drug Delivery Systems.
TL;DR: Protein nanoparticles can be generated using proteins, and are prepared through emulsion, electrospray, and desolvation methods, and the corresponding advantages and disadvantages are compared.
Journal ArticleDOI
Biodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors.
Agnese Gagliardi,Elena Giuliano,Eeda Venkateswararao,Massimo Fresta,Stefania Bulotta,Vibhudutta Awasthi,Donato Cosco +6 more
TL;DR: In this paper, the use of polymeric nanoparticles as drug delivery systems of anticancer compounds, their physico-chemical properties and their ability to be efficiently localized in specific tumor tissues have been described.
Journal ArticleDOI
Bioavailability of nutraceuticals: Role of the food matrix, processing conditions, the gastrointestinal tract, and nanodelivery systems
TL;DR: The physicochemical and enzymatic processes involved in food digestion are described, highlighting the role of each stage of gastrointestinal tract (mouth, stomach, and intestine) in nutraceuticals bioaccessibility, and several types of bioactive-loaded nanocarriers that improve the bioavailability of nutr pharmaceuticals are focused on.
References
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Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Biodegradable polymeric nanoparticles based drug delivery systems
TL;DR: The impact of nanoencapsulation of various disease related drugs on biodegradable nanoparticles such as PLGA, PLA, chitosan, gelatin, polycaprolactone and poly-alkyl-cyanoacrylates is highlighted.
Journal ArticleDOI
Nanocapsule formation by interfacial polymer deposition following solvent displacement
TL;DR: In this paper, an attempt was made to elucidate the mechanisms of formation in terms of interfacial turbulence between two unequilibrated liquid phases involving flow, diffusion and surface tension decrease (Marangoni effect).
Journal ArticleDOI
'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption.
Ruxandra Gref,Martin Lück,P. Quellec,M Marchand,Edith Dellacherie,Stephan Harnisch,Torsten Blunk,Rainer H. Müller +7 more
TL;DR: 2-D PAGE studies showed that plasma protein adsorption on PEG-coated PLA nanospheres strongly depends on the PEG molecular weight (Mw), which could be useful in the design of long circulating intravenously injectable biodegradable drug carriers endowed with protein resistant properties and low phagocytic uptake.
Journal ArticleDOI
PEGylated Nanoparticles for Biological and Pharmaceutical Applications
TL;DR: The potential utility of multimolecular assembly derived from heterobifunctional PEGs and block copolymers were explored to systematically modify the properties of metal and semiconductor nanostructures by controlling their structure and their surface properties, making them extremely attractive for use in biological and biomedical applications.