Reward circuitry responsivity to food predicts future increases in body mass: moderating effects of DRD2 and DRD4.
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TLDR
This novel prospective fMRI study indicates that responsivity of reward circuitry to food increases risk for future weight gain, but that genes that impact dopamine signaling capacity moderate the predictive effects, suggesting two qualitatively distinct pathways to unhealthy weight gain based on genetic risk.About:
This article is published in NeuroImage.The article was published on 2010-05-01 and is currently open access. It has received 311 citations till now.read more
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Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
TL;DR: Functional neuroimaging studies conducted in the past decade that have expanded the understanding of the involvement of the PFC in drug addiction are focused on.
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A Heuristic for Developing Transdiagnostic Models of Psychopathology Explaining Multifinality and Divergent Trajectories
TL;DR: This article proposes a heuristic for developing transdiagnostic models that can guide theorists in explicating how a trans Diagnostic risk factor results in both multifinality and divergent trajectories and illustrates this heuristic using research on rumination.
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Reward mechanisms in obesity: new insights and future directions.
TL;DR: Recent advances in the understanding of the brain circuitries that regulate hedonic aspects of feeding behavior will be reviewed and emerging evidence suggesting that obesity and drug addiction may share commonHedonic mechanisms will also be considered.
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Body mass correlates inversely with inhibitory control in response to food among adolescent girls: an fMRI study.
TL;DR: Functional magnetic resonance imaging is used to investigate neural activations during a food-specific go/no-go task in adolescent girls ranging from lean to obese and suggests that hypofunctioning of inhibitory control regions and increased response of food reward regions are related to elevated weight.
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Prediction as a Humanitarian and Pragmatic Contribution from Human Cognitive Neuroscience
John D. E. Gabrieli,John D. E. Gabrieli,Satrajit S. Ghosh,Satrajit S. Ghosh,Susan Whitfield-Gabrieli +4 more
TL;DR: Findings in which initial brain measures are correlated with or predict future education, learning, and performance in children and adults; criminality; health-related behaviors; and responses to pharmacological or behavioral treatments are reviewed.
References
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Explicit and implicit attitudes towards food and physical activity in childhood obesity
Mietje Craeynest,Geert Crombez,Jan De Houwer,Benedicte Deforche,Ann Tanghe,Ilse De Bourdeaudhuij +5 more
TL;DR: Children and adolescents with obesity had a more pronounced positive implicit attitude towards food in general than the control group, and this finding has implications for prevention, treatment and further research.
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Neural system for controlling the contents of object working memory in humans
Jennifer K. Roth,John T. Serences,John T. Serences,Susan M. Courtney,Susan M. Courtney,Susan M. Courtney +5 more
TL;DR: In this paper, the authors used functional magnetic resonance imaging to show that when WM contents were updated, regardless of stimulus type (faces or houses), a frontoparietal network showed transient increases in activation.
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Neural substrates for the processing of cognitive and affective aspects of taste in the brain.
TL;DR: This review of the literature will show how taste information is conveyed through the central gustatory pathways to the cortical gustatory area and is processed in terms of qualitative and quantitative aspects.
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DRD4 VNTR polymorphism is associated with transient fMRI-BOLD responses to smoking cues.
TL;DR: These brain imaging results suggest that DRD4 VNTR polymorphism is related to transient brain responses to smoking cues in regions subserving executive and somatosensory processes.
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Body mass index and marijuana use.
TL;DR: Findings provide support for overeating as competition for drugs and alcohol in brain reward sites during morbid obesity/weight management inbrain reward sites.