Journal ArticleDOI
Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn.
B N Christensen,Edward R. Perl +1 more
TLDR
HIGH-THRESHOLD MECHANORECEPTORS and their centrally projecting myelinated fibers make up a functionally distinct group of cutaneous sensory units that have been suggested as part of the afferent apparatus for pain resulting from mechanical damage to the skin.Abstract:
HIGH-THRESHOLD MECHANORECEPTORS and their centrally projecting myelinated fibers make up a functionally distinct group of cutaneous sensory units that have been suggested as part of the afferent apparatus for pain resulting from mechanical damage to the skin (3, 17). The argument for their relation to pain was based on two points: 1) the ability of such afferent elements, unique among those with medullated fibers, to provide signals differentiating noxious from innocuous mechanical events affecting the skin; and 2) the well-established correlation between pain and activity in thin myelinated afferent fibersread more
Citations
More filters
Book ChapterDOI
Diencefalo: talamo dorsale
TL;DR: I termini talamo dorsale e ventrale derivano dalla loro disposizione topografica nella parete laterale del diencefalo durante lo sviluppo.
Book ChapterDOI
Introduction to Section II
TL;DR: In the cat, the common laboratory animal used in neurophysiological experiments, and especially when the lumbo-sacral spinal cord is considered, most of the fine afferent fibres come from the skin, with a much smaller proportion from the subcutaneous and deep tissues and teh pelvic viscera.
Journal ArticleDOI
[Clinical experiences of non-destructive transcutaneous afferent electrical stimulation therapy for pain relief (author's transl)].
Ryotaro Kuroda,Kaoru Taguchi,Fumiharu Akai,Masaru Watanabe,Masahiko Ioku,Kentaro Koshino,Heitaro Mogami,Nobuhiro Kanai +7 more
TL;DR: Good benefits are to be expected from this non-destructive treatment for chronic pain in combination with medication and/or destructive treatment of transcutaneous afferent electrical stimulation for various types of intractable pain.
Book ChapterDOI
History of Pain
TL;DR: The period of enlightenment re-established scientific methods in Europe, mainly discussing the question whether pain is a specific or non-specific sensation, and holistic treatment of pain was reintroduced with the advent of cognitive behavioural treatment and recently mindfulness.
Journal ArticleDOI
In memoriam Donald D. Price: 1942 to 2016
TL;DR: Donald D. Price was one of the rare individuals who moved fluidly from very basic studies of nociceptive mechanisms in animals to studies of psychological mechanisms in human patients suffering from chronic pain.
References
More filters
Journal ArticleDOI
Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli.
P Bessou,Edward R. Perl +1 more
TL;DR: In an attempt to learn more about the range of behavior associated with the terminals of cutaneous C fibers, a number of randomly sele,cted units were surveyed for responses to a variety of graded stimuli.
Journal ArticleDOI
Myelinated afferent fibres responding specifically to noxious stimulation of the skin
Paul R. Burgess,Edward R. Perl +1 more
TL;DR: The characteristics of receptors from the hairy skin of the hind limb of cat were studied by recording from single primary afferent fibres with fine micropipettes with distinctive features of 513 fibres conducting under 51 m/sec.
Journal ArticleDOI
Myelinated afferent fibres innervating the primate skin and their response to noxious stimuli.
TL;DR: The functional characteristics of cutaneous receptors in the squirrel monkey were determined by recording discharges of single myelinated afferent fibres in peripheral nerves with micro‐electrodes or from fine filaments prepared by dissection.
Related Papers (5)
Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli.
P Bessou,Edward R. Perl +1 more