Journal ArticleDOI
The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
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TLDR
Method has been applied to a study of hydroxyproline distribution in cell particulates, tissue fluids, and purified plant and animal proteins, and significant amounts of hydroXYproline were found in crystalline preparations of pepsin, elastase.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1961-05-01. It has received 3756 citations till now. The article focuses on the topics: Hydroxyproline & Imino acid.read more
Citations
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Effect of proteoglycan depletion on T2 mapping in rat patellar cartilage.
Astrid Watrin-Pinzano,Jean-Pierre Ruaud,Pierre Olivier,Laurent Grossin,Patrick Gonord,Alain Blum,Patrick Netter,Geneviève Guillot,Pierre Gillet,Damien Loeuille +9 more
TL;DR: In rat patellar cartilage, T2 mapping permits detection of slight or severe proteoglycan depletion and concurrent changes of extracellular matrix when age-matched samples are compared.
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Greener approach to leather tanning process: d-Lysine aldehyde as novel tanning agent for chrome-free tanning
TL;DR: In this paper, a greener and eco-friendly method to leather tanning process has been developed in the present investigation, which is based on d-Lysine aldehyde complex.
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Wound healing and T-lymphocytes.
TL;DR: Combined anti-T-helper/effector and T-suppressor/cytotoxic depletion resulted in improved wound-healing parameters, which suggests that there is a Thy-1.2+, L3T4-, Lyt2- subpopulation of T lymphocytes which normally stimulates wound healing.
Journal ArticleDOI
Pekin duckling and broiler chicken Pectoralis muscle structure and composition
TL;DR: A series of experiments was conducted to determine muscle fiber type, area, and distribution, and muscle total collagen, color, proximate composition, total fatty acid profile, calories, and cholesterol content for Pekin duckling and broiler chicken Pectoralis muscle.
Journal ArticleDOI
Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
Jérôme Avouac,Jérôme Avouac,Katrin Palumbo,Michal Tomcik,Pawel Zerr,Clara Dees,Angelika Horn,Britta Maurer,Alfiya Akhmetshina,Christian Beyer,Anika Sadowski,Holm Schneider,Shunichi Shiozawa,Oliver Distler,Georg Schett,Yannick Allanore,Jörg H W Distler +16 more
TL;DR: Up-regulation of c-Jun and c-Fos was detected in mouse models of SSc and in the skin and dermal fibroblasts of patients with SSc, indicating AP-1 is up-regulated in a TGFβ-dependent manner in SSc.
References
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Journal ArticleDOI
The determination of hydroxyproline.
Robert E. Neuman,Milan A. Logan +1 more
TL;DR: A short and simple calorimetric method is here described that is applicable to the determination of hydroxyproline in hydrolysates of 40 to 100 y of collagen with a reproducibility of f2 per cent and an accuracy of f1 per cent as judged by recovery of hydroXYproline from elastin hydrolysate and from an amino acid mixture simulating collagen.
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[Microdetermination of hydroxyproline with chloramine-T and p-dimethylaminobenzaldehyde].
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Growth and sexual differentiation of hydra in mass culture
W. F. Loomis,H. M. Lenhoff +1 more
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Appendix—Notes on a modification of the Neuman & Logan method for the determination of the hydroxyproline
Journal ArticleDOI
Formation of collagen hydroxyproline in vitro
N. M. Green,D. A. Lowther +1 more
TL;DR: Stetten (1949) suggested that free hydroxyproline was not an intermediate in collagen biosynthesis and that hydroxylation of the proline residues occurred at the protein or peptide stage.