Journal ArticleDOI
The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
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TLDR
Method has been applied to a study of hydroxyproline distribution in cell particulates, tissue fluids, and purified plant and animal proteins, and significant amounts of hydroXYproline were found in crystalline preparations of pepsin, elastase.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1961-05-01. It has received 3756 citations till now. The article focuses on the topics: Hydroxyproline & Imino acid.read more
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Proteoglycan-type I collagen fibril interactions in bone and non-calcifying connective tissues.
J. E. Scott,M. Haigh +1 more
TL;DR: The association of proteogtycans with type I collagen fibrils in skin, tendon, cornea and bone has been determined by electron microscopy using an electrondense dye, Cupromeronic blue, in the critical electrolyte concentration mode, backed up by biochemical analysis and digestion by hyaluronidase or keratanase.
Journal ArticleDOI
Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice.
James C. Lee,Paul Kinniry,Evguenia Arguiri,Matthew Serota,Stathis Kanterakis,Shampa Chatterjee,Charalambos C. Solomides,Prashanthi Javvadi,Constantinos Koumenis,Keith A. Cengel,Melpo Christofidou-Solomidou +10 more
TL;DR: Dietary curcumin ameliorates radiation-induced pulmonary fibrosis and increases mouse survival while not impairing tumor cell killing by radiation.
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Possible involvement of mast cells in collagen remodeling in the late phase of cutaneous wound healing in mice.
TL;DR: Results suggest that mast cells accumulated at the wound edge may participate in tissue remodeling in the late phase of wound healing.
Journal ArticleDOI
Role of green tea polyphenols in the inhibition of collagenolytic activity by collagenase
TL;DR: Inhibitory effect of green tea polyphenols viz., catechin and epigallocatechin gallate (EGCG) on the action of collagenase against collagen has been probed in this study and CD spectral studies showed significant changes in the secondary structure of collagen enzyme on treatment with higher concentration of cate chin and EGCG.
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Alterations in left ventricular diastolic function in conscious dogs with pacing-induced heart failure.
Kazuo Komamura,R P Shannon,Ares Pasipoularides,T. Ihara,A S Lader,T A Patrick,S. P. Bishop,Stephen F. Vatner +7 more
TL;DR: P pacing-induced heart failure in conscious dogs is characterized by major alterations in diastolic function which are reversible with normalization of increased loading condition.
References
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Journal ArticleDOI
The determination of hydroxyproline.
Robert E. Neuman,Milan A. Logan +1 more
TL;DR: A short and simple calorimetric method is here described that is applicable to the determination of hydroxyproline in hydrolysates of 40 to 100 y of collagen with a reproducibility of f2 per cent and an accuracy of f1 per cent as judged by recovery of hydroXYproline from elastin hydrolysate and from an amino acid mixture simulating collagen.
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[Microdetermination of hydroxyproline with chloramine-T and p-dimethylaminobenzaldehyde].
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Growth and sexual differentiation of hydra in mass culture
W. F. Loomis,H. M. Lenhoff +1 more
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Appendix—Notes on a modification of the Neuman & Logan method for the determination of the hydroxyproline
Journal ArticleDOI
Formation of collagen hydroxyproline in vitro
N. M. Green,D. A. Lowther +1 more
TL;DR: Stetten (1949) suggested that free hydroxyproline was not an intermediate in collagen biosynthesis and that hydroxylation of the proline residues occurred at the protein or peptide stage.