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Journal ArticleDOI

The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.

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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.
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This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.

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Journal ArticleDOI

Single-cell transcriptome profiling of the human endometrium of patients with recurrent implantation failure

TL;DR: This study provides deeper insights into endometrial microenvironment disorder of RIF that are potentially applicable to improving the etiological diagnosis and therapeutics of unexplained RIF.
Journal ArticleDOI

Mixed double-embryo transfer: A promising approach for patients with repeated implantation failure.

TL;DR: MDET was found to be significantly superior to double blastocyst transfer in patients with repeated implantation failure and could be regarded as an appropriate approach to improve in vitro fertilization success rates in RIF patients.
Journal ArticleDOI

Vitrification of Human Oocytes and its Contribution to In Vitro Fertilization Programs.

TL;DR: Oocyte vitrification offered the possibility of gestation in more than one attempt after just one controlled hyperstimulation, and apart from alleviating the financial burden on patients, vitrification of oocytes may result in a feasible solution for the problems generated by abandoned frozen embryos.
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Live birth after transfer of a single euploid vitrified-warmed blastocyst according to standard timing vs. timing as recommended by endometrial receptivity analysis.

TL;DR: In this article , an endometrial receptivity analysis (ERA) was used to evaluate the effect of unsuccessful frozen embryo transfer (FET) on live birth in patients with and without a history of FET failure.
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Autologous platelet-rich plasma improves the endometrial thickness and live birth rate in patients with recurrent implantation failure and thin endometrium

TL;DR: In this article , the authors evaluated the effects of intrauterine platelet-rich plasma infusion on endometrial thickness and pregnancy outcomes in a population of patients with either recurrent implantation failure (RIF), thin endometrium (TE), or both.
References
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Journal ArticleDOI

Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women

TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
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A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature

TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
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Investigation and treatment of repeated implantation failure following IVF-ET

TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
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Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology

TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.
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