Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
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Book ChapterDOI
Wiederholtes Implantationsversagen – diagnostische und therapeutische Ansätze
Frank Nawroth,Michael Ludwig +1 more
TL;DR: Die Implantation als erfolgreicher Beginn einer sich etablierenden Schwangerschaft stellt das Ergebnis eines durch zahlreiche Faktoren von Embryo and Endometrium beeinflussten Zusammenspiels dar.
Book ChapterDOI
Patients with Uterine Factor Infertility: General
TL;DR: The group AUFI includes congenital pathologies such as uterine agenesis or hypoplasia and also acquired conditions such as hysterectomy post-partum or difficult-to-treat diseases like leiomyomas or neoplasia of the uterus.
Journal ArticleDOI
Endometrial gland-specific progestagen-associated endometrial protein and cilia gene splicing changes in recurrent pregnancy loss
TL;DR: In this paper , a comprehensive catalogue of cilia and progestagen-associated endometrial protein (PAEP) gene isoforms and relative exon usage was provided to determine whether an endometrium gland-specific transcriptome and splicing profile are altered in women with recurrent pregnancy loss.
Journal ArticleDOI
Zooming in on the endometrial factor of recurrent implantation failure.
TL;DR: In this paper, the authors highlight the implications of these endometrial pathologies and their association with recurrent implantation failure (RIF) and highlight the importance of the endometrium as a receptive site for implantation.
References
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Journal ArticleDOI
Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women
Said Talbi,A.E. Hamilton,Kim Chi Vo,Suzana Tulac,Michael Toft Overgaard,Chrysoula Dosiou,N Le Shay,C.N. Nezhat,R Kempson,Bruce A. Lessey,Nihar R. Nayak,Linda C. Giudice +11 more
TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
Journal ArticleDOI
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization.
TL;DR: It is suggested that IVF treatment that is preceded by endometrial biopsy doubles the chance for a take-home baby.
Journal ArticleDOI
Investigation and treatment of repeated implantation failure following IVF-ET
TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI
Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology
Anne Riesewijk,Julio Martín,Roselinde van Os,José A. Horcajadas,Jan Polman,Antonio Pellicer,Sietse Mosselman,Carlos Simón +7 more
TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.