Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
Citations
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Journal ArticleDOI
Endometrial factor testing is a useful tool in clinical infertility management
TL;DR: The application of transcriptomics to endometrial biology enables an objective identification of the personalized period during which the maternal endometrium is receptive to an embryo, known as the window of implantation as discussed by the authors .
Posted ContentDOI
Endometrial receptivity revisited: endometrial transcriptome adjusted for tissue cellular heterogeneity
Marina Suhorutshenko,Viktorija Kukushkina,Agne Velthut-Meikas,Signe Altmäe,Maire Peters,Reedik Mägi,Kaarel Krjutškov,Mariann Koel,Juan F. Martinez-Blanch,Francisco M. Codoñer,Felipe Vilella,Carlos Simón,Andres Salumets,Triin Laisk +13 more
TL;DR: The results suggest new mechanisms involved in endometrial maturation involving genes like LINC01320, SLC8A1 and GGTA1P, described for the first time in context ofendometrial receptivity, are suggested.
Dissertation
Impacto sobre la expresión génica del endometrio de la maduración final ovocitaria con un agonista de la GnRH y diferentes protocolos de soporte de fase lútea
TL;DR: Tesis Doctoral leida en la Universidad Rey Juan Carlos de Madrid (RJCD) as discussed by the authors, 2013. Directores de la Tesis: Juan Antonio Garcia Velasco y Maria Cerrillo Martinez
Posted ContentDOI
Role of T cells in intrauterine administration of activated peripheral blood mononuclear cells in recurrent implantation failure.
Guillaume Ricaud,Cathy Vaillancourt,Véronique Blais,Marjorie Disdier,Fabien Joao,Bruno Johnson,Moncef Benkhalifa,Pierre Miron,Jacques Bernier +8 more
TL;DR: In this article, the role of T cells to promote human endometrial receptivity was evaluated for patients with unexplained recurrent implantation failure (RIF) by using autologous peripheral blood mononuclear cells (PBMC).
Journal ArticleDOI
No endometrial receptivity assay of enlightenment for recurrent implantation failure.
Allison Bosch,Heather S. Hipp +1 more
TL;DR: In this paper , a negative pregnancy test after embryo transfer is frustrating for both patient and physician, especially when the potential predictors of success, such as screened euploid embryo and normal uterine cavity, auger well.
References
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Journal ArticleDOI
Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women
Said Talbi,A.E. Hamilton,Kim Chi Vo,Suzana Tulac,Michael Toft Overgaard,Chrysoula Dosiou,N Le Shay,C.N. Nezhat,R Kempson,Bruce A. Lessey,Nihar R. Nayak,Linda C. Giudice +11 more
TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
Journal ArticleDOI
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization.
TL;DR: It is suggested that IVF treatment that is preceded by endometrial biopsy doubles the chance for a take-home baby.
Journal ArticleDOI
Investigation and treatment of repeated implantation failure following IVF-ET
TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI
Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology
Anne Riesewijk,Julio Martín,Roselinde van Os,José A. Horcajadas,Jan Polman,Antonio Pellicer,Sietse Mosselman,Carlos Simón +7 more
TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.