Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
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15 years of transcriptomic analysis on endometrial receptivity: what have we learnt?
Soumaya Messaoudi,Imane El. Kasmi,Amélie Bourdiec,Kimberley Crespo,Laurence Bissonnette,Cécile Le Saint,François Bissonnette,Isaac Jacques Kadoch +7 more
TL;DR: The dynamic transition from a non-receptive to a receptive endometrium is still poorly understood and several reports have shown that ER is defined by specific changes in factors involved in adhesion, invasion, survival, growth, differentiation, decidualization and immuno-modulation.
Journal ArticleDOI
First PGT-A using human in vivo blastocysts recovered by uterine lavage: Comparison with matched IVF embryo controls
Santiago Munné,Steven T. Nakajima,Sam Najmabadi,Mark V. Sauer,Marlane Angle,José L. Rivas,Laura V Mendieta,Thelma M. Macaso,S.S. Sawarkar,Alexander Nadal,Kajal Choudhary,Camran Nezhat,Sandra A. Carson,John E. Buster +13 more
TL;DR: This is the first study to recover in vivo derived human blastocysts following ovarian stimulation for embryo genetic characterization and Lavage blastocyst scores had significantly higher morphology scores than the control IVF embryos as determined by chi-square analysis.
Journal ArticleDOI
MiR-27a-3p and miR-124-3p, upregulated in endometrium and serum from women affected by Chronic Endometritis, are new potential molecular markers of endometrial receptivity.
Cinzia Di Pietro,Salvatore Caruso,Rosalia Battaglia,Marco Iraci Sareri,Alessandro La Ferlita,Fabrizio Strino,Gabriele Bonaventura,Maurizio Di Mauro,Maria Luisa Barcellona,Vincenzo Perciavalle,Michele Purrello,Antonio Cianci +11 more
TL;DR: Chronic endometritis is usually asymptomatic and different studies demonstrated the relation with infertility and recurrent pregnancy loss, but there is no evidence about the involvement of microRNAs in the pathology.
Journal ArticleDOI
Uterine Fluid in Pregnancy: A Biological and Clinical Outlook
TL;DR: It is proposed that these molecules may also carry information that mirrors maternal environmental exposure and possibly relay such information to the embryo via uterine fluid, generating long-term epigenetic effects on the offspring via embryonic and placental programming.
Journal ArticleDOI
Preparation of the Endometrium for Frozen Embryo Transfer: A Systematic Review.
Sezcan Mumusoglu,Mehtap Polat,İrem Y Özbek,Gurkan Bozdag,Evangelos G. Papanikolaou,Sandro C. Esteves,Peter Humaidan,Hakan Yarali +7 more
TL;DR: In this paper, the authors investigated the effect of inter-personal variation in serum progesterone levels with an impact on reproductive outcomes, despite the use of the same dose and route of progrostone administration.
References
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Journal ArticleDOI
Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women
Said Talbi,A.E. Hamilton,Kim Chi Vo,Suzana Tulac,Michael Toft Overgaard,Chrysoula Dosiou,N Le Shay,C.N. Nezhat,R Kempson,Bruce A. Lessey,Nihar R. Nayak,Linda C. Giudice +11 more
TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
Journal ArticleDOI
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization.
TL;DR: It is suggested that IVF treatment that is preceded by endometrial biopsy doubles the chance for a take-home baby.
Journal ArticleDOI
Investigation and treatment of repeated implantation failure following IVF-ET
TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI
Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology
Anne Riesewijk,Julio Martín,Roselinde van Os,José A. Horcajadas,Jan Polman,Antonio Pellicer,Sietse Mosselman,Carlos Simón +7 more
TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.