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Journal ArticleDOI

The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.

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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.
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This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.

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Journal ArticleDOI

The future of reproductive medicine centers.

TL;DR: It is predicted that women who have frozen oocytes at a younger age will return to make embryos at age 40 to 50 years, a trend the authors already see in their daily practice.
Journal ArticleDOI

Histological endometrial dating: a reliable tool for personalized frozen-thawed embryo transfer in patients with repeated implantation failure in natural cycles

TL;DR: In this article , the authors evaluated the clinical availability and stability of histological endometrial dating as a tool for personalized frozen-thawed embryo transfer (pFET) in patients with repeated implantation failure (RIF) in natural cycles.
Journal ArticleDOI

Observations on clinical assessment of endometrial receptivity.

TL;DR: In this article , the authors examined the investigation of the endometrial cavity before embryo transfer using various techniques, including hysteroscopy, endometrium biopsy using immunohistochemistry and molecular microarray, and ultrasound imaging.
Journal ArticleDOI

History of Recurrent Implantation Failure is Associated With the Incidence of Adverse Perinatal Outcomes in Singleton Live Births Following Frozen-Thawed Embryo Transfer Cycles

TL;DR: Women with a history of RIF were associated with an increased risk of LBW, PTB, and PROM in singleton live births after FET cycles, and multiple intrauterine procedures were independent risk factors for PROM.
Book ChapterDOI

Endometrium Gene Expression and Epigenetic Regulation in Reproductive Failure

TL;DR: Genomic study of the endometrium may shed light on the regulation of embryo implantation and how the process is disrupted in women with reproductive failure.
References
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Journal ArticleDOI

Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women

TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
Journal ArticleDOI

A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature

TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI

Investigation and treatment of repeated implantation failure following IVF-ET

TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI

Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology

TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.
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